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Table 4 Mean (± SD) for CS Score, respiratory rate, heart rate and SpO2 for patients in each group at 0,30, 60 and 120 min of assessment

From: Nebulised hypertonic saline (3 %) among children with mild to moderately severe bronchiolitis - a double blind randomized controlled trial

  Intervention 0.9 % NS + L-Epi (n = 50) Intervention 3 % HS + L-Epi (n = 50) p value 95 % confidence interval lower limits – upper limits (mean)
CS score, n, Mean ± S.D; range
0 min 5.2 ± 1.1 (3–9) 5.3 ± 1.6; (3–9) 0.57 −0.73; 0.41 (−0.15)
30 min 4.9 ± 1.1; (3–8) 4.3 ± 2.0; (2–8) 0.10 −0.11; 1.21 (0.55)
60 min 3.2 ± 1.0; (1–6) 2.2 ± 1.2; (1–7) 0.001 0.52; 1.43 (0.97)
120 min 2.9 ± 0.8; (1–5) 1.7 ± 0.9; (1–7) 0.001 0.77; 1.52 (1.14)
Respiratory rate, breaths/minute, Mean ± S.D; range
0 min 49.0 ± 2.0; (46–58) 49.1 ± 2.5; (46–60) 0.79 −1.01;0.81 (−0.12)
30 min 47.4 ± 1.7; (46–54) 46.6 ± 2.1; (42–56) 0.04 0.04; 1.61 (0.81)
60 min 45.3 ± 1.4; (42–50) 43.5 ± 2.0; (40–52) 0.001 1.13; 2.57 (1.85)
120 min 43.6 ± 2.6; (40–48) 40.7 ± 2.0; (38–49) 0.001 1.97; 3.86 (2.91)
Oxygen saturation,%, Mean ± S.D; range
0 min 93.5 ± 0.7; (90–94) 93.4 ± 0.8 (90–95) 0.69 −0.22; 0.40 (0.09)
30 min 93.8 ± 0.8; (91–96) 94.2 ± 1.2; (90–96) 0.07 −0.79; 0.06 (−0.36)
60 min 94.9 ± 0.9; (92–97) 95.8 ± 1.1; (92–98) 0.001 −1.34; −0.48 (−0.97)
120 min 95.6 ± 1.0; (93–98) 97.0 ± 1.0; (93–99) 0.001 −1.77; −0.91 (−1.14)
Heart rate, beats/minute, Mean ± S.D; range
0 min 149.7 ± 7.1; (132–166) 148.7 ± 7.5; (132–168) 0.49 −1.94; 3.98 (0.80)
30 min 149.7 ± 7.9; (130–164) 147.1 ± 9.1; (130–164) 0.13 −0.93; 6.04 (2.91)
60 min 145.2 ± 6.4; (130–156) 142.6 ± 7.2; (126–156) 0.06 −0.20; 5.30 (2.55)
120 min 141.8 ± 5.8; (126–154) 138.3 ± 6.6; (124–152) 0.006 1.02; 6.03 (3.53)