Glucosuria as an early marker of late-onset sepsis in preterms: a prospective cohort study

BMC Pediatrics

Table 1 Characteristics of the study population and suspected sepsis episodes

	Patients with suspected infection
	n = 123
Gestational age, weeks^+days	29⁺¹ (2⁺¹)
Birthweight, g	1187 (345)
Male sex, n (%)	70 (56.9 %)
Died during admission, n (%)	1 (0.8 %)
Age at onset of suspected infection, days	12 (7–18)
Follow-up, days	24 (14–35)
Respiratory symptoms
(Increase in) apnea, bradycardia and/or cyanotic spells	56 (45.5 %)
Increased respiratory support^a	53 (43.1 %)
Circulatory symptoms
Pallor/gray skin	61 (49.6 %)
Capillary refill time > 2 s	49 (39.8 %)
Tachycardia	44 (35.8 %)
General symptoms
Temperature instability	86 (69.9 %)
Lethargy	56 (45.5 %)
Irritability	14 (11.4 %)
Laboratory values
C-Reactive protein (mg/l)	2 (0–10)
Leucocytes (10^E9/l)	14.0 (8.9–18.0)
Risk factors
CVC in last 24 h	39 (31.7 %)
Mechanical ventilation	12 (9.8 %)

Mean (standard deviation) for gestational age, birth weight. For age at onset and follow-up in days median (p25 and p75) are given because of skewed distribution
Data from patients who experienced more than one episode of suspected infection are from their first episode. For characteristics of sepsis episodes numbers (percentage) are given, except for “Laboratory values” where median (p25-p75) are presented. CVC central venous catheter
^aIncreased in respiratory support: intensifying the modus, i.e. low flow, CPAP or endotracheal ventilation and/or degree of respiratory support)

ISSN: 1471-2431