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Table 1 Perinatal and neonatal characteristics of all cooled neonates with HIE (n = 142)

From: Subcutaneous fat necrosis in neonates with hypoxic ischaemic encephalopathy registered in the Swiss National Asphyxia and Cooling Register

  With SCFN (n = 4) Without SCFN (n = 138) p-value
Gestational age [days] 278 [268–301] 279 [244–302] ns
Birth weight [grams] 3340 [3190–3920] 3200 [1790–4700] ns
Head circumference [cm] 34.75 [34.0–35.5] 34.50 [30.5–40.0] ns
APGAR score 5 min 4 [1–7] 3 [0–10] ns
APGAR score 10 min 7 [4–8] 5 [0–10] ns
Umbilical artery pH 6.96 [6.90–7.05] 6.92 [6.54–7.43] ns
Worst pHa 7.02 [6.90–7.19] 6.88 [6.50–7.46] ns
Worst lactate[mmol/l]
[mmol/l]a
18 [15.0–19.0] 15 [1.80–28.0] ns
Sarnat Score on admission 1.5 [1.0–2.0] 2.0 [1.0–3.0] ns
Thompson Score on admission 4.5 [3.0–6.0] 9.0 [2.0–15.0] ns
Sarnat Score after TH 1.0 [1.0–1.0] 1.0 [1.0–3.0] ns
Thompson Score after TH 1.0 [1.0–1.0] 3.0 [1.0–17.0] 0.05
  1. All values given as median and range [in parenthesis]
  2. SCFN subcutaneous fat necrosis, TH therapeutic hypothermia, ns not significant
  3. aworst pH and worst lactate within first 60 min of life