Fragile X syndrome screening in Chinese children with unknown intellectual developmental disorder

BMC Pediatrics

Table 2 Changes in repeat size during the maternal transmission in 24 mother-son pairs with different AGG structures

Maternal AGG interruption	Number of mother-boy pair	Mean of CGG size in mother*	Mean of CGG expansion during maternal transmission**	Number of mother-boy pair showing CGG expansion (%)
1	10	29	0.20	2 (20 %)
2	14	30.2	0.79	9 (64 %)

* The minimum CGG repeat was determined for mothers with heterozygous FMR1 alleles; ** The maximum CGG expansion was calculated for mothers with heterozygous FMR1 alleles; * The difference in CGG size between mother and son CGG genotypes. See Supplementary Table 2 for detailed FMR1 genotyping information

ISSN: 1471-2431