From: Clinical features and outcomes of invasive pneumococcal disease in a pediatric intensive care unit
Survival (n = 45) | Death (n = 3) | Total (n = 48) | p | |
---|---|---|---|---|
Males | 18 | 1 | 19 | 1.00 |
Age (years) | 0.18 | |||
< 2 | 9 | 2 | 11 | |
2–5 | 29 | 1 | 30 | |
6–17 | 7 | 0 | 7 | |
Received vaccination | 11 | 0 | 11 | 1.00 |
Symptoms and signs1 | ||||
Fever | 45 | 3 | 48 | |
Cough and rhinorrhea | 43 | 2 | 45 | 0.18 |
Vomiting without abdominal pain | 15 | 3 | 18 | 0.05 |
Altered mental status | 10 | 3 | 13 | 0.02 |
GCS <12 | 8 | 3 | 11 | 0.01 |
Seizure | 9 | 3 | 12 | 0.01 |
Initial laboratory values | ||||
WBC count (1000 cells/mm3) | 14.7 ± 12.6 | 4.6 ± 2.1 | 14.1 ± 12.4 | 0.16 |
CRP (mg/L) | 243 ± 107 | 178 ± 84 | 240 ± 107 | 0.32 |
Positive blood culture result | 26 | 3 | 29 | 0.27 |
Disease category | 0.01 | |||
Pneumonia | 38 | 0 | 38 | |
Meningitis | 7 | 3 | 10 | |
Length of hospital stay | 22.9 ± 13.4 | 1.7 ± 1.2 | 21.6 ± 14.0 | <0.01 |
in PICU | 11.8 ± 12.1 | 1.7 ± 1.2 | 11.2 ± 11.9 | <0.01 |