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Table 2 Postnatal respiratory management between LISA and control group

From: A pilot study of less invasive surfactant administration in very preterm infants in a Chinese tertiary center

 

LISA (n=47)

Intubation (n=43)

P value

Time of first surfactant dose (min)

65 (20.7)

63 (25.3)

0.68

Two or more dose surfactant

8 (17.0)

5 (11.4)

0.44

pneumothorax

4 (8.9)

3 (7.0)

0.79

Supplemental O2 at age of 28 days

12 (25.5)

11 (25.6)

0.81

BPD

6 (12.8)

6 (14.0)

0.87

Mild

5 (10.6)

5 (11.6)

0.85

Moderate or severe, n (%)

1 (2.1)

1 (2.3)

0.51

PDA treat with medical therapy

28 (59.6)

26 (60.5)

0.93

PDA treat with surgery

1 (2.1)

0 (0)

0.34

IVH grades I or II

23 (48.9)

21 (47.7)

0.91

IVH grades III or IV

1 (2.1)

0 (0)

0.34

PVL

1 (2.1)

1 (2.3)

0.51

ROP > stage 2

0

0

ns

Respiratory support

Mechanical ventilation during the first 72 hr, n (%)*

8 (17.0)

10 (23.3)

0.44

Mechanical ventilation days

6.7 (3.5)

7.4 (4.3)

0.40

nCPAP, n (%)#

47 (100)

43 (100)

ns

nCPAP days

10.9 (7.8)

12.3 (8.4)

0.41

Both MV and nCPAP days

13.2 (6.7)

15.9 (5.1)

0.03

Oxygen, n (%)*

38 (80.8)

34 (79.1)

0.83

Oxygen days

20.7 (5.2)

22.3 (6.9)

0.22

In hospital days

68.5 (17.3)

70.1 (22.5)

0.70

Died during the first 28 days

1 (2.1)

0 (0)

0.34

  1. #need NCPAP during the hospitalization.
  2. *need oxygen by mask or nasal tube during the hospitalization.