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Preterm injury
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• Cranial ultrasound scan (cUSS)
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• Normal
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• Grade III IVH
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• Grade IV IVH
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• Grade I/II Intraventricular haemorrhage (IVH)
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• Non-cystic Periventricular leucomalacia (PVL)
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• Periventricular haemorrhage infarction (PVHI)
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• Ventricular index (VI) < 13 mm Term equivalent age (TEA) OR
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• VI 13-15 mm TEA OR
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• Cystic PVL
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• VI < 97th percentile for corrected gestational age (CGA)
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• VI >97th percentile but < 4 mm above 97th percentile for CGA
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• Subcortical leucomalacia
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• VI at TEA >15 mm OR
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• VI >4 mm above 97th percentile for CGA
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• Basal ganglia (BG) lesions
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• Focal infarction
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Term hypoxic ischaemic encephalopathy
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• Magnetic resonance imaging (MRI)
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• Focal subtle abnormalities of BG with normal appearance of the posterior limb of the internal capsule (PLIC)
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• Multi-focal lesions in BG with equivocal or abnormal signal intensity within PLIC
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• Widespread abnormalities involving all Basal ganglia-Thalamus (BGT) structures and PLIC
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• cUSS where MRI unavailable
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• Periventricular white matter changes difficult to differentiate from normal appearances and therefore not classified as abnormal
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• Small focal lesions of without loss of grey matter (GM)/WM differentiation.
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• Larger areas of abnormality with loss of GM/WM differentiation, consistent with infarction
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• Changes confined to cerebral cortex and subcortical white matter (WM)
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• Central grey matter hyperechogenicity +/− more extensive cortical and subcortical hyperechogenicity
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Term infarction
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• MRI (cUSS where MRI unavailable)
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• Focal, non-territorial infarct
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• Territorial infarct
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