High mortality in HIV-infected children diagnosed in hospital underscores need for faster diagnostic turnaround time in prevention of mother-to-child transmission of HIV (PMTCT) programs

Table 1 Differences in Mortality and time to ART initiation between Hospital and PMTCT

	PMTCT		Hospital
Outcome of Interest	N	Median (IQR) or n (%)	N	Median (IQR) or n (%)	HR (95%CI)	p-value
Overall Mortality	37	6 (16%)	62	24 (39%)	3.1 (1.3, 7.6)	0.01
Mortality pre-ART	37	2 (5%)	62	10 (16%)	2.9 (0.64, 13)	0.2
Mortality post-ART	33*	4 (12%)	47*	14 (30%)	2.9 (0.94, 8.7)	0.06
Time to ART initiation (enrollment to ART initiation)	37		62		0.80 (0.51, 1.3)	0.3
Median days to ART initiation	33*	8 (7-20)**	47*	14 (7-20)**

*Among 37 infants diagnosed in PMTCT, 2 died and 2 were lost to follow-up prior to initiating ART; among 62 infants diagnosed in hospital, 10 died, 1 was lost to follow-up, and 4 were withdrawn prior to initiating ART.
**Median time to initiation of ART among those children who initiated ART.

ISSN: 1471-2431