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Table 2 Description of potential biological and health predictors of low IQ and unadjusted associations*

From: Early life determinants of low IQ at age 6 in children from the 2004 Pelotas Birth Cohort: a predictive approach

Characteristic

Rate n (%)

Low IQ n (%)

Unadjusted OR (95% CI)

All

3523 (100)

594 (16.9)

 

Intended pregnancy (n = 3521)

  

p = 0.0000

Intended

1554 (44.1)

206 (13.3)

1

Unintended

1967 (55.9)

386 (19.6)

1.6 (1.3–1.9)

Prenatal care visits (n = 3337)

  

p = 0.0000

<6

541 (16.2)

158 (29.2)

2.5 (2.1–3.2)

≥6

2796 (83.8)

390 (14.0)

1

Maternal hospitalization during pregnancy (n = 3522)

  

p = 0.5425

No

3147 (89.3)

534 (17.0)

1

Yes

375 (10.7)

59 (15.7)

0.9 (0.7–1.2)

Maternal mental disorder during the child’s first year of life (n = 3375)

  

p = 0.0000

No

2189 (64.9)

296 (13.5)

1

Yes

1186 (35.1)

268 (22.6)

1.9 (1.6–2.2)

Type of delivery (n = 3522)

  

p = 0.0000

Vaginal

1920 (54.5)

392 (20.4)

1.8 (1.5–2.2)

Cesarean section

1602 (45.5)

201 (12.6)

1

Gestational age (n = 3521)

  

p = 0.0009

<37 weeks

470 (13.4)

105 (22.3)

1.5 (1.2–1.9)

≥37 weeks

3051 (86.6)

488 (16.0)

1

Birth weight (n = 3522)

  

p = 0.0003

<2500 g

304 (8.6)

75 (24.7)

1.7 (1.3–2.3)

≥2500 g

3218 (91.4)

518 (16.1)

1

Health condition at birth (n = 3514)

  

p = 0.0078

No

3111 (88.5)

503 (16.2)

1

Yes

403 (11.5)

87 (21.6)

1.4 (1.1–1.8)

Child’s gender (n = 3522)

  

p = 0.0003

Female

1701 (48.3)

246 (14.5)

1

Male

1821 (51.7)

347 (19.1)

1.4 (1.2–1.7)

Child hospitalization during the first year of life (n = 3424)

  

p = 0.0000

No

2801 (81.8)

434 (15.5)

1

Yes

623 (18.2)

140 (22.5)

1.6 (1.3–2.0)

Duration of breastfeeding (n = 3512)

  

p = 0.0000

<1 month

364 (10.4)

98 (26.9)

2.2 (1.7–2.9)

1–11 months

1792 (51.0)

298 (16.6)

1.2 (1.0–1.5)

≥12 months

1356 (38.6)

194 (14.3)

1

Duration of exclusive breastfeeding (n = 3474)

  

p = 0.0000

<1 month

1265 (36.4)

258 (20.4)

2.8 (1.8–4.3)

1–5 months

1899 (54.7)

301 (15.9)

2.1 (1.4–3.1)

≥6

310 (8.9)

26 (8.4)

1

Weight-for-age deficit during the first year of life (n = 3522)

  

p = 0.0000

No

3099 (88.0)

476 (15.4)

1

Yes

423 (12.0)

117 (27.7)

2.1 (1.7–2.7)

Height-for-age deficit during the first year of life (n = 3523)

  

p = 0.0000

No

2918 (82.8)

436 (14.9)

1

Yes

604 (17.2)

157 (26.0)

2.0 (1.6–2.5)

Head circumference-for-age deficit during the first year of life (n = 3522)

  

p = 0.0000

No

3211 (91.2)

497 (15.5)

1

Yes

311 (8.8)

96 (30.9)

2.4 (1.9–3.2)

Weight-for-height deficit during the first year of life (n = 3521)

  

p = 0.0634

No

3334 (94.7)

551 (16.5)

1

Yes

187 (5.3)

41 (21.9)

1.4 (1.0–2.0)

Mother’s self-rated health (n = 3421)

  

p = 0.0000

Excellent/very good

1269 (37.1)

137 (10.8)

1

Good/fair/poor

2152 (62.9)

437 (20.3)

2.1 (1.7–2.6)

Maternal perception of the child’s health status (n = 3424)

  

p = 0.0000

Excellent/very good

2119 (61.9)

253 (11.9)

1

Good/fair/poor

1305 (38.1)

321 (24.6)

2.4 (2.0–2.9)

  1. *Logistic regression analysis in children age 6. The 2004 Pelotas Birth Cohort Study.
  2. CI = confidence intervals; OR = odds ratios; IQ = intelligence quotient.