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Table 3 Odds ratio estimates and 95% confidence intervals for the association of vitamin D status and ever diagnosed atopic diseases

From: Serum 25(OH)D concentrations and atopic diseases at age 10: results from the GINIplus and LISAplus birth cohort studies

Outcome: ever diagnosis

Outcome

 

OR (CI)

1. Quartile

2. Quartile

3. Quartile

4. Quartile

Continuous [per 10 nmol/l]

Asthma male

Cases/Non-diseased (% Cases)

34/265 (11%)

35/297 (11%)

25/282 (8%)

39/303 (11%)

133/1147 (10%)

Adjusted model1

1

0.84 (0.50;1.40)

0.65 (0.37;1.13)

0.97 (0.59;1.61)

1.00 (0.92;1.07)

Asthma female

Cases/Non-diseased (% Cases)

15/295 (5%)

22/281 (7%)

22/289 (7%)

17/278 (6%)

76/1143 (6%)

Adjusted model1

1

1.54 (0.78;3.06)

1.48 (0.74;2.93)

1.21 (0.59;2.50)

1.02 (0.92;1.13)

Eczema

Cases/Non-diseased (% Cases)

173/430 (29%)

196/430 (31%)

184/420 (30%)

195/433 (31%)

748/1713 (30%)

Adjusted model2

1

1.12 (0.87;1.44)

1.09 (0.84;1.40)

1.14 (0.89;1.46)

1.05* (1.01;1.09)

Hay fever or allergic rhinitis

Cases/Non-diseased (% Cases)

99/504 (16%)

119/507 (19%)

117/487 (19%)

121/507 (19%)

456/2005 (19%)

Adjusted model2

1

1.13 (0.84;1.53)

1.16 (0.86;1.57)

1.15 (0.85;1.56)

1.02 (0.98;1.07)

  1. 1Outcome = Vitamin D concentration + age + study + breastfeeding + BMI + highest parental education + family history.
  2. 2Outcome = Vitamin D concentration + age + sex + location of study + study + breastfeeding + BMI + highest parental education + single parent status + family history.
  3. The OR estimates and 95% CI for the association of vitamin D status (serum 25(OH)D concentration in quartiles or as continuous variable [10 nmol/l]) and ever diagnosed atopic diseases are displayed. The asterisk indicate significant results at p < 0.05.