Skip to main content

Table 2 Odds ratio estimates and 95% confidence intervals for the association of vitamin D status and atopic diseases diagnosed at the age of 10 years

From: Serum 25(OH)D concentrations and atopic diseases at age 10: results from the GINIplus and LISAplus birth cohort studies

Outcome: at the age of 10 years

Outcome

 

OR (CI)

1. Quartile

2. Quartile

3. Quartile

4. Quartile

Continuous [per 10 nmol/l]

Asthma male

Cases/Non-diseased (% Cases)

21/271 (7%)

16/309 (5%)

14/282 (5%)

15/312 (5%)

66/1174 (5%)

Adjusted model1

1

0.59 (0.30;1.16)

0.57 (0.28;1.17)

0.58 (0.29;1.17)

0.92 (0.82;1.03)

Asthma female

Cases/Non-diseased (% Cases)

4/301 (1%)

8/290 (3%)

8/285 (3%)

9/280 (3%)

29/1156 (2%)

Adjusted model1

1

2.20 (0.66;7.50)

2.07 (0.61;7.05)

2.58 (0.76;8.57)

1.12 (0.97;1.30)

Eczema

Cases/Non-diseased (% Cases)

18/569 (3%)

36/567 (6%)

38/536 (7%)

31/580 (5%)

123/2252 (5%)

Adjusted model2

1

2.01* (1.12;3.60)

2.27* (1.27;4.06)

1.82 (1.00;3.31)

1.09* (1.01;1.17)

Hay fever or allergic rhinitis

Cases/Non-diseased (% Cases)

57/536 (10%)

77/539 (13%)

66/513 (11%)

67/548 (11%)

267/2136 (11%)

Adjusted model2

1

1.28 (0.89;1.86)

1.12 (0.76;1.64)

1.07 (0.73;1.57)

0.98 (0.93;1.04)

  1. 1Outcome = Vitamin D concentration + age + study + breastfeeding + BMI + highest parental education + family history.
  2. 2Outcome = Vitamin D concentration + age + sex + location of study + study + breastfeeding + BMI + highest parental education + single parent status + family history.
  3. The OR estimates and 95% CI for the association of vitamin D status (serum 25(OH)D concentration in quartiles or as continuous variable [10 nmol/l]) and atopic diseases diagnosed at the age of 10 years are displayed. The asterisk indicate significant results at p < 0.05.