From: Association between coenzyme Q10 and glucose transporter (GLUT1) deficiency
Patient | Reference values | |
---|---|---|
Blood | ||
Lactate | 1.8-2.6 (2.2) | 0.5-1.7 mmol/L |
Alanine | 300-691 (560) | 150-270 μmol/L |
Cholesterol | 4.0 | < 5.2 mmol/L |
CoQ (baseline) | 0.33 | 0.45-1.1 μmol/L |
CoQ (after treatment) | 3.9-7.8 (5.5) | 0.45-1.1 μmol/L |
Cerebrospinal fluid | ||
Glucose | 1.9 | 2.2-3.4 mmol/L |
Lactate | 1.07 | 1.1-2.2 mmol/L |
Muscle biopsy | ||
CoQ content | 76 | 115-450 nmol/g protein |
Complex I + III* | 149 | 107-560 mU/citrate synthase U |
Complex II + III* | 82 | 75-149 mU/citrate synthase U |
Fibroblast | ||
CoQ content (incubated with glucose) | 78 | 100-150 nmol/g protein |
CoQ content (incubated with galactose) | 123 | 100-150 nmol/g protein |