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Table 5 Reporting of details on DMCs in trials that mentioned DMCs (n = 89)

From: A systematic review of the reporting of Data Monitoring Committees' roles, interim analysis and early termination in pediatric clinical trials

Parameter Pediatric Journals (n = 26) General Journals (n = 63)
Members Identity   
   Reported 16 (62) 51 (81)
   Unclear or Not Reported 10 (38) 12 (19)
Member Affiliations   
   Reported 6 (23) 19 (30)
   Unclear or Not Reported 20 (77) 44 (70)
Independence   
   Reported 10 (39) 23 (37)
   Unclear or Not Reported 16 (61) 40 (63)
Monitored outcomes   
   Reported 11 (42) 39 (62)
   Unclear or Not Reported 15 (58) 24 (38)
Vigilance of other trial conduct parameters   
   Reported 5 (9) 12 (19)
   Unclear or Not Reported 21 (81) 51 (81)
Blinding to Primary Outcome Data   
   Reported 7 (27) 18 (29)
   Unclear or Not Reported 19 (73) 45 (71)
Predefined Stopping Guidelines   
   Reported 5 (19) 18 (29)
   Unclear or Not Reported 21 (81) 45 (71)
  1. N (%)