Table 1 Key variables, measures proposed, data sources, and time of administration
From: Co-bedding as a Comfort measure For Twins undergoing painful procedures (CComForT Trial)
Variables | Measures | Method/Sources | Time of administration |
|---|---|---|---|
Pain response | Premature Infant Pain Profile (PIPP) | Videotape of facial responses | Baseline, warming heelstick and recovery |
Physiologic recovery | Heart rate, Oxygen saturation | Somté software | Baseline, warming heelstick and recovery |
Heart rate variability | Cardiac monitoring | Somté software | Baseline, warming heelstick and recovery |
Hormonal stress response | Cortisol | Sorbette oral swab | Prior to heelstick (basal) and 20 minutes after (stress) the heel stick |
Frequency of 24% sucrose administration | Count | Chart medication record, confirmed with videotape recording | 2 minute prior and during intervention |
Co-twin Response | All measures identical to the twin undergoing heelstick, except sucrose count | Identical measures, except sucrose count | Baseline, warming heelstick and recovery |
Safety surveillance | Caregiver error Infection rate | Institutional adverse event and infection control surveillance | Quarterly |
Clinical Stability | Supplemental oxygen Incidence of apnea Bradycardia | Chart review | Baseline, warming heelstick and recovery |