Failure of early empirical AB regimen - N (% of all study patients) | 32 (11.6) |
I Proven EOS with etiologic pathogen(s) resistant to initial empirical AB therapy - n (% of treatment failure) | 10 (31.3) |
died within 7 days | 4 |
II clinical EOS and death (with autopsy confirming the diagnosis of congenital infection) and/or major sepsis-related complication (IVH III-IV) within the first week of life - n (% of treatment failure) | 11a (34.4) |
died within 7 days | 10 |
III clinical EOS and change of initial empirical AB therapy within 72 h with new regimen continued for more than 72 h - n (% of treatment failure) | 11 (34.4) |