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Table 2 Performance of the HIV algorithm compared to HIV test results

From: Paediatric HIV management at primary care level: an evaluation of the integrated management of childhood illness (IMCI) guidelines for HIV

n = 1064a

Classified as suspected symptomatic HIV

Identified as HIV exposed

Any HIV classification (either HIV exposed OR suspected symptomatic HIV)

#

171

201

313

# confirmed HIV positive

54

43

69

Sensitivity

(95% CI)

71.1%

(59.5% - 80.9%)

56.6%

(44.7% - 67.9%)

90.8%

(81.9% - 96.2%)

Specificity

(95% CI)

88.1%

(85.9% - 90.1%)

84.0%

(81.6% - 86.2%)

75.3%

(72.5% - 77.9%)

PPV

(95% CI)

31.6%

(24.7% - 39.15)

21.4%

(15.9% - 27.7%)

22.0%

(17.6% - 27.1%)

NPV

(95% CI)

97.5%

(96.3% - 98.4%)

96.2%

(94.7% - 97.4%)

99.1%

(98.1% - 99.6%)

Likelihood ratio +

(95% CI)

5.99

(4.79 - 7.48)

3.54

(2.77 - 4.51)

3.67

(3.22 - 4.18)

  1. a comprises all children where an HIV test result is known