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Table 2 Comparison of clinical and laboratory parameters in patients with proven sepsis (sepsis with positive blood culture and/or detection of bacterial DNA in blood) and patients with non-proven sepsis (no bacterial agent found)

From: Comparison of broad range 16S rDNA PCR and conventional blood culture for diagnosis of sepsis in the newborn: a case control study

Maternal parameters Proven sepsis Non-proven sepsis p
Maternal fever > 38°C 1/11 10/20 0.02
Maternal antibiotics 2/11 8/20 0.15
Premature rupture of membranes 3/11 8/20 0.25
Normal vaginal delivery 5/11 5/20 0.16
Infant parameters    
Gestational age (GA) < 37 weeks 0/11 2/20 0.40
Irritability 6/11 6/20 0.13
Fever > 38°C 2/11 5/20 0.32
Heart rate >160 beats per minute 2/11 3/20 0.37
Respiratory rate > 60 per minute 3/11 8/20 0.21
Apgar at 5 min < 8 1/11 3/20 0.40
Feeding difficulties 2/11 4/20 0.32
Capillary refill time > 3 seconds 1/11 7/20 0.11
Oxygen saturation (SaO2) < 88% 3/11 3/20 0.26
BE < -5 0/11 0/20 1.0
Leukocyte count < 5 0/11 1/20 0.47
Platelets < 100 2/11 0/20 0.12
Blood glucose < 2,5 mmol/l 0/11 3/20 0.25
CRP mg/l 49.3 ± 41.3 42.7 ± 29.1 0.60
Highest CRP mg/l 71.7 ± 41.6 70.3.6 ± 35.5 0.92