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Table 13 Laboratory values for all infants who were HIV-uninfected at birth (negative by PCR at 6 weeks of age), by HIV exposure status at the first birth visit.

From: Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol

Laboratory measures

HIV-unexposed infant

HIV-exposed infant

p-value

 

N

Mean

95% CI

N

Mean

95% CI

 
   

Lower

Upper

  

Lower

Upper

 

Values at first research assessment after birth

Hemoglobin g/dL

275

19.4

10.6

28.8

1625

18.3

9.9

27.9

< .0001

Hematocrit %

275

58.0

33.0

85.8

1622

54.2

29.4

79.4

< .0001

Platelets 103/μL

274

247.5

78.0

450.0

1619

239.7

75.0

458.0

0.2

White blood cells 103/μL

272

15.9

6.5

33.0

1593

15.5

5.7

30.5

0.3

Values at research assessment at age 4–6 weeks of age

Hemoglobin g/dL

278

11.9

8.1

18.9

1432

11.6

7.6

17.9

0.02

Hematocrit %

278

34.8

22.7

53.4

1432

33.8

22.3

51

0.04

Platelets 103/μL

277

383.4

104

704

1427

369.5

89

697

0.2

White blood cells 103/μL

276

10.1

5.1

17.4

1418

10.9

5.0

21.3

0.006

*ALT (SGPT) IU/liter

123

16.4

5

38

1429

22.7

5

63

0.005

  1. * ALT (SGPT) = alanine aminotransferase (serum glutamic pyruvic transaminase)
  2. HIV-exposed means that these infants were born to HIV-infected mothers, while HIV-unexposed infants were born to HIV-uninfected mothers. Alanine aminotransferase (serum glutamic pyruvic transaminase) was not performed at the birth visit.