Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings

Table 5 Predictors of Symptom Score improvement: results of stepwise multiple linear regression analysis

Variable	0–6 months (N = 380)			0–12 months (N = 360)
	Adjusted R² change	B (95% confidence interval)	P-value	Adjusted R² change	B (95% confidence interval)	P-value
Intercept		0.31 (-1.21 to 1.82)	0.690		0.67 (-0.57 to 1.90)	0.290
Symptom Score at enrolment (0–10)	0.17	0.67 (0.54 to 0.81)	< 0.001	0.20	0.71 (0.58 to 0.84)	< 0.001
Disease Score at enrolment (0–10)	0.03	-0.18 (-0.32 to -0.05)	0.007	0.02	-0.21 (-0.34 to -0.08)	0.002
Main AM therapy modality medical*	0.01	0.81 (0.20 to 1.42)	0.010	---	---	---
Previous treatment by physician*	0.01	0.60 (0.11 to 1.09)	0.016	---	---	---
Disease duration (years)	0.01	-0.10 (-0.19 to -0.02)	0.018	0.02	-0.14 (-0.23 to -0.05)	0.002
Physiotherapy, occupational therapy or play therapy in months 0–6 (sessions)	0.01	-0.03 (-0.05 to -0.003)	0.029	---	---	---
Main diagnosis F00–F99 Mental and behavioural disorder*	---	---	---	0.02	-0.65 (-1.08 to -0.22)	0.003
Enrolment by general practitioner*	---	---	---	0.01	0.58 (0.14 to 1.02)	0.010
	Total R² 0.23			Total R² 0.26
Analysis of variance for model		F-value	P-value		F-value	P-value
		19,727	< 0.001		26,641	< 0.001

Adjusted R²: Adjusted coefficient of multiple determination. B: regression coefficient. *: 0 = no, 1 = yes. ---: Variable not included in the model.

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