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Table 2 Biochemical parameters in all groups

From: Bone growth during rapamycin therapy in young rats

Serum Parameters

2 weeks

4 weeks

 

Rapamycin, N = 6

Control, N = 6

Rapamycin, N = 7

Control, N = 7

Intact PTHa (pg/mL)

40 ± 22

68 ± 34

32 ± 21c

90 ± 37

Calciuma (mg/dL)

10 ± 0.6

10 ± 0.4

9.8 ± 0.1

10 ± 0.1

Phosphorusa (mg/dL)

12 ± 0.2b

12 ± 0.5

10 ± 0.5

11 ± 0.7

Creatininea (mg/dL)

0.2 ± 0.04b

0.2 ± 0.03b

0.3 ± 0.04

0.3 ± 0.07

IGF-Ia (ng/mL)

708 ± 222b

867 ± 180b

1028 ± 256c

1318 ± 297

  1. aObtained at the time of sacrifice
  2. bp < 0.003, 2 weeks versus 4 weeks (same group)
  3. cp < 0.006, rapamycin versus control (4 weeks)
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BMC Pediatrics

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