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Table 2 The growth responses (SDS) of patients with PSIS or transient GHD to GH treatment

From: Diagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency

SDS

PSIS

Transient GHD

P

 

(n = 53)

(n = 19)

 

First year

   

Growth rate

3.8 ± 2.6

1.3 ± 2.2

0.0007

Height change

1.2 ± 1.0

0.48 ± 0.7

<0.0001

Second year

   

Growth rate

1.8 ± 2.4

0.26 ± 1.3

0.006

Height change

0.47 ± 0.5

0.18 ± 0.3

<0.03

Third year

   

Growth rate

0.77 ± 1.7

0.05 ± 1.3

NS

Height change

0.2 ± 0.4

0.14 ± 0.3

NS

Height change over three years

1.9 ± 1.1

0.8 ± 1.0

0.0002

 

(n = 30)

(n = 12)

 

Adult height

-1.0 ± 0.9

-1.8 ± 0.8

<0.02

Height change from diagnosis

1.7 ± 1.2

1.08 ± 0.8

0.05

Mean ± SD