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Table 1 Patient characteristics

From: Diagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency

Group

N (boys/girls)

Age years

(a)

Height SDS

Target height SDS

(b)

Growth rate SDS

(c)

BMI SDS

GH peak ng/ml

(a)

IGF-1 zs

1. GHD with PSIS

53 (31/22)

4.7 ± 4.0

[0.02;17]

-2.5 ± 1.4

[-6.2; 0.8]

-0.2 ± 0.8

[-1.7;1.5]

-2.2 ± 1.4

[-4.3;1.6]

0.19 ± 1.7

[-2.4;6.7]

2.6 ± 1.8

0.0;6.6

-3.8 ± 0.9

-5.5;-2.3

2. Transient GHD

19 (9/10)

9.2 ± 3.0

[1.1;14.0]

-2.8 ± 0.8

[-4.4;-1.5]

-0.8 ± 0.9

[-2.6;0.9]

-1.2 ± 1.0

[-3.5;0.1]

0.32 ± 1.4

[-1.9;3.5]

4.9 ± 1.2

3.0;6.7

-3.2 ± 0.9

-4.8;-1.8

  1. means ± SD [ranges]
  2. Group 1 compared to Group 2: (a) P < 0.0001; (b) P < 0.02; (c) < 0.003
  3. Among the 29 Group 1 patients with other hypothalamic-pituitary deficiencies, 4 had only a TSH deficiency, 10 had TSH and adrenocorticotropin hormone deficiencies, 2 had TSH and gonadotropin deficiencies, and 13 had a complete anterior pituitary deficiency.