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Table 1 Patient characteristics

From: Diagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency

Group N (boys/girls) Age years
(a)
Height SDS Target height SDS
(b)
Growth rate SDS
(c)
BMI SDS GH peak ng/ml
(a)
IGF-1 zs
1. GHD with PSIS 53 (31/22) 4.7 ± 4.0
[0.02;17]
-2.5 ± 1.4
[-6.2; 0.8]
-0.2 ± 0.8
[-1.7;1.5]
-2.2 ± 1.4
[-4.3;1.6]
0.19 ± 1.7
[-2.4;6.7]
2.6 ± 1.8
0.0;6.6
-3.8 ± 0.9
-5.5;-2.3
2. Transient GHD 19 (9/10) 9.2 ± 3.0
[1.1;14.0]
-2.8 ± 0.8
[-4.4;-1.5]
-0.8 ± 0.9
[-2.6;0.9]
-1.2 ± 1.0
[-3.5;0.1]
0.32 ± 1.4
[-1.9;3.5]
4.9 ± 1.2
3.0;6.7
-3.2 ± 0.9
-4.8;-1.8
  1. means ± SD [ranges]
  2. Group 1 compared to Group 2: (a) P < 0.0001; (b) P < 0.02; (c) < 0.003
  3. Among the 29 Group 1 patients with other hypothalamic-pituitary deficiencies, 4 had only a TSH deficiency, 10 had TSH and adrenocorticotropin hormone deficiencies, 2 had TSH and gonadotropin deficiencies, and 13 had a complete anterior pituitary deficiency.