Skip to main content

Table 2 Craniopharyngioma 1 year after surgery

From: Childhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index

  Hypothalamic involvement    
Grade 0 1 2 0 vs 1 0 vs 2 1 vs 2
     P P P
Height, SDS 0.13 ± 1.3 (7) -1.6 ± 1.1 (8) -0.55 ± 1.3 (12) <0.04   
BMI, zs 2.7 ± 1.1 (7) 2.5 ± 1.8 (8) 4.0 ± 1.3 (12)   <0.05  
Changes in weight, Kg 5.8 ± 4.9 (7) 7.2 ± 5.3 (8) 16.3 ± 7.4 (12)   <0.007 <0.02
Changes in weight, SDS 1.0 ± 1.2 (7) 1.2 ± 0.9 (8) 2.5 ± 1.4 (12)   <0.05 <0.04
Glucose, mmol/L NA 3.9 ± 1.2 (2) 4.6 ± 0.7 (7)    
Insulin, mIU/L 10.1 ± 9.0 (2) 6.1 ± 3.7 (5) 47 ± 58 (10)    <0.04
HOMA NA 0.9 ± 0.3 (2) 7.1 ± 9.0 (7)    
IGF-1, zs -4.3 ± 0.6 (2) -2.8 ± 2.0 (6) -2.4 ± 0.8 (10)   <0.05  
Leptin, μg/L 14.2 ± 14 (2) 32 ± 14 (4) 61 ± 26 (10)    <0.04
sOB-R, μg/L NA 30 ± 5.3 (4) 28 ± 7.2 (5)    
Free leptin index NA 113 ± 63 (4) 279 ± 102 (5)    0.05
Ghrelin, ng/L NA 994 ± 263 (4) 722 ± 126 (6)    
  1. mean ± SD; NA: not available.
  2. Number in parentheses indicate the effectives
  3. The biological data were collected 6–18 months after surgery