Table 2 Craniopharyngioma 1 year after surgery
Hypothalamic involvement | ||||||
|---|---|---|---|---|---|---|
Grade | 0 | 1 | 2 | 0 vs 1 | 0 vs 2 | 1 vs 2 |
P | P | P | ||||
Height, SDS | 0.13 ± 1.3 (7) | -1.6 ± 1.1 (8) | -0.55 ± 1.3 (12) | <0.04 | ||
BMI, zs | 2.7 ± 1.1 (7) | 2.5 ± 1.8 (8) | 4.0 ± 1.3 (12) | <0.05 | ||
Changes in weight, Kg | 5.8 ± 4.9 (7) | 7.2 ± 5.3 (8) | 16.3 ± 7.4 (12) | <0.007 | <0.02 | |
Changes in weight, SDS | 1.0 ± 1.2 (7) | 1.2 ± 0.9 (8) | 2.5 ± 1.4 (12) | <0.05 | <0.04 | |
Glucose, mmol/L | NA | 3.9 ± 1.2 (2) | 4.6 ± 0.7 (7) | |||
Insulin, mIU/L | 10.1 ± 9.0 (2) | 6.1 ± 3.7 (5) | 47 ± 58 (10) | <0.04 | ||
HOMA | NA | 0.9 ± 0.3 (2) | 7.1 ± 9.0 (7) | |||
IGF-1, zs | -4.3 ± 0.6 (2) | -2.8 ± 2.0 (6) | -2.4 ± 0.8 (10) | <0.05 | ||
Leptin, μg/L | 14.2 ± 14 (2) | 32 ± 14 (4) | 61 ± 26 (10) | <0.04 | ||
sOB-R, μg/L | NA | 30 ± 5.3 (4) | 28 ± 7.2 (5) | |||
Free leptin index | NA | 113 ± 63 (4) | 279 ± 102 (5) | 0.05 | ||
Ghrelin, ng/L | NA | 994 ± 263 (4) | 722 ± 126 (6) | |||