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Table 5 Incidence of AOM and TMP in vaccinated and comparison groups, including sensitivity analyses

From: Pneumococcal vaccination and otitis media in Australian Aboriginal infants: comparison of two birth cohorts before and after introduction of vaccination

  AOM TMP
  Baseline analysis Sensitivity analysis Baseline analysis Sensitivity analysis
  Vaccinated Comparison Vaccinated Comparison Vaccinated Comparison Vaccinated Comparison
No. of participants 90 37 97 51 94 41 97 51
Examinations per year 11.53 11.80 10.24 10.20 10.77 11.70 10.03 10.20
No. of episodes 104 45 139 87 35 23 37 33
No. with 0 episodes (%) 29 (32) 9 (24) 24 (25) 6 (12) 70 (74) 30 (73) 71 (73) 34 (67)
No. with 1 episode (%) 28 (31) 14 (38) 28 (29) 17 (33) 16 (17) 3 (7) 18 (19) 6 (12)
No. with >1 episodes (%) 33 (37) 14 (38) 44 (45) 28 (55) 8 (8) 8 (19) 8 (8) 11 (22)
Unadjusted incidence 1.87/yr 2.05/yr 1.68/yr 2.02/yr 0.55/yr 0.82/yr 0.44/yr 0.77/yr
Adjusted incidence* 1.83/yr 2.03/yr 1.62/yr 2.02/yr 0.47/yr 0.75/yr 0.39/yr 0.75/yr
Absolute rate reduction -0.20/yr   -.40/yr   -0.28/yr   -0.36/yr  
  1. * Adjusted in multivariate poisson model considering repeated events.
  2. Absolute rate reduction is the incidence in the vaccinated minus incidence in the comparison group.
  3. Baseline analyses of incidence of AOM and TMP included participants if the first examination was at less than 4 months and less than 6 months respectively, and included follow-up data if repeated examinations were less than 2 months apart. Sensitivity analyses included participants with any age at first examination, and included follow-up data if repeated examinations were less than 4 months apart.