Skip to main content

Table 4 Birth year adjusted analyses of the association between infant characteristics and childhood leukemia.

From: Parental and infant characteristics and childhood leukemia in Minnesota

 

Sub-cohort

ALL

AML

 

No. (%)

No. (%)

HR

95% CI

No. (%)

HR

95% CI

Child gender

       

   female

4242 (49)

227 (41)

ref.

43 (49)

ref.

   male

4501 (51)

332 (59)

1.38

1.16–1.64

44 (51)

0.97

0.64–1.49

   missing

7 (0)

1 (0)

  

0 (0)

  

Birth weight

       

   Per 1 sd increase (per 581 grams)

8710

555

1.12

1.03–1.23

87

1.33

1.06–1.66

Birth weight category

       

   < 2496 g

406 (5)

29 (5)

1.49

0.96–2.30

2 (2)

0.86

0.19–3.94

   2496–3117 g

1746 (20)

83 (15)

ref.

10 (11)

ref.

   3118–3458 g

2192 (25)

117 (21)

1.13

0.84–1.51

23 (26)

1.85

0.88–3.91

   3459–3798 g

2142 (25)

152 (27)

1.48

1.12–1.95

20 (23)

1.65

0.77–3.54

   3799–4309 g

1796 (21)

137 (25)

1.59

1.20–2.11

27 (31)

2.65

1.27–5.49

   ≥ 4309 g

428 (5)

37 (7)

1.82

1.22–2.73

5 (6)

1.96

0.66–5.78

   missing

40 (0)

5 (1)

  

0 (0)

  

Size for gestational age*

       

   small

271 (3)

20 (4)

1.23

0.77–1.97

2 (2)

0.78

0.19–3.22

   average

5708 (72)

343 (67)

ref.

54 (65)

ref.

   large

1905 (24)

151 (29)

1.30

1.07–1.59

27 (33)

1.51

0.95–2.40

   missing

314 (4)

27 (5)

  

1 (1)

  

Gestational age category*

       

   <37 weeks

657 (8)

43 (8)

1.00

0.72–1.38

4 (5)

0.56

0.20–1.53

   37–42 weeks

6938 (88)

446 (86)

ref.

1 (1)

ref.

   >42 weeks

311 (4)

28 (5)

1.47

0.98–2.19

2 (2)

0.59

0.14–2.43

   missing

292 (4)

24 (4)

  

1 (1)

  

One minute Apgar score +

       

   0–7

1798 (23)

144 (29)

1.32

1.08–1.61

26 (33)

1.62

1.01–2.60

   >7

5884 (77)

359 (71)

ref.

53 (67)

ref.

   missing

336 (4)

34 (6)

  

4 (5)

  

Five minute Apgar score +

       

   0–7

275 (4)

14 (3)

0.77

0.44–1.33

4 (5)

1.47

0.53–4.08

   >7

7394 (96)

488 (97)

ref.

75 (95)

ref.

   missing

349 (4)

35 (7)

  

4 (5)

  

Assisted ventilation category †

       

   any

79 (2)

5 (2)

0.93

0.37–2.34

0 (0)

ND‡

   none

4548 (98)

300 (98)

ref.

41 (100)

  

   missing

356 (7)

31 (9)

  

6 (13)

  

Congenital abnormality

       

   any

122 (1)

10 (2)

1.30

0.68–2.51

1 (1)

ND

   none

8100 (99)

505 (98)

ref.

81 (99)

  

   missing

528 (6)

45 (8)

  

5 (6)

  
  1. *collected 1980–2004.
  2. +collected 1981–2004.
  3. †collected 1989–2004.
  4. ‡ND = not determined
Back to article page

BMC Pediatrics

ISSN: 1471-2431

Contact us