Table 2 Impact table to show the predicting power of specific hypoxia-related genes on CMS (CMS-score ≥ 12) in the fathers of Andean children
In Children | Adjust for HPH3 | Adjust HPH3 | ||||||
|---|---|---|---|---|---|---|---|---|
At Cerro | STB | P | Cerro | STB | P | Cerro | STB | P |
log_EPO | -0.07 | 0.79 | log_EPO | -0.36 | 0.32 | log_HPH3 | 0.88 | 0.05 |
log_HPH1 | 0.02 | 0.94 | log_HPH1 | 0.06 | 0.84 | log_HPH3 | 0.75 | 0.07 |
log_HPH2 | 0.21 | 0.44 | log_HPH2 | 0.20 | 0.53 | log_HPH3 | 0.75 | 0.07 |
log_HPH3 | 0.74 | 0.07 | ||||||
log_VEGFC | -0.05 | 0.85 | log_VEGFC | -0.38 | 0.27 | log_HPH3 | 0.96 | 0.05 |
log_PDK1 | -0.30 | 0.38 | log_PDK1 | -2.69 | 0.18 | log_HPH3 | 2.82 | 0.08 |
log_PDP1 | 0.16 | 0.55 | log_PDP1 | -0.36 | 0.38 | log_HPH3 | 1.00 | 0.06 |
log_HIF1A | 0.67 | 0.07 | log_HIF1A | 0.51 | 0.19 | log_HPH3 | 0.61 | 0.17 |
log_HIF1B | -0.43 | 0.24 | log_HIF1B | -1.28 | 0.07 | log_HPH3 | 1.84 | 0.08 |
log_HIF2A | 0.61 | 0.08 | log_HIF2A | 0.78 | 0.13 | log_HPH3 | 1.00 | 0.11 |
log_HIF3A | 0.01 | 0.98 | log_HIF3A | -0.17 | 0.62 | log_HPH3 | 0.77 | 0.06 |
log_POK2 | 0.02 | 0.94 | log_POK2 | -0.20 | 0.53 | log_HPH3 | 0.80 | 0.06 |
log_PDP2 | 0.06 | 0.83 | log_PDP2 | -0.18 | 0.58 | log_HPH3 | 0.80 | 0.06 |
log_PDK3 | -0.37 | 0.26 | log_PDK3 | -0.91 | 0.04 | log_HPH3 | 1.39 | 0.04 |
log_PDK4 | -0.21 | 0.45 | log_PDK4 | -0.20 | 0.51 | log_HPH3 | 0.73 | 0.07 |
log_PDHE1A1 | -0.25 | 0.39 | log_PDHE1A1 | -0.98 | 0.06 | log_HPH3 | 1.54 | 0.05 |
log_GADPH | -0.20 | 0.48 | log_GADPH | -1.01 | 0.08 | log_HPH3 | 1.62 | 0.05 |
log_EPOR | 0.24 | 0.40 | log_EPOR | -0.38 | 0.43 | log_HPH3 | 1.02 | 0.07 |
log_GLUT1 | -0.15 | 0.59 | log_GLUT1 | -0.53 | 0.15 | log_HPH3 | 1.05 | 0.05 |
log_LDHA | missing | |||||||
log_CATD | missing | |||||||
Adjust for LDHA | Adjust LDHA | |||||||
At Lima | Lima | STB | P | Lima | STB | P | ||
log_EPO | -0.13 | 0.61 | log_EPO | 0.13 | 0.70 | log_LDHA | -0.64 | 0.09 |
log_HPH1 | 0.29 | 0.28 | log_HPH1 | 0.45 | 0.20 | log_LDHA | -0.69 | 0.07 |
log_HPH2 | -0.38 | 0.18 | log_HPH2 | -0.20 | 0.51 | log_LDHA | -0.50 | 0.16 |
log_HPH3 | 0.12 | 0.67 | log_HPH3 | 0.40 | 0.34 | log_LDHA | -0.84 | 0.08 |
log_VEGFC | missing | log_VEGFC | ||||||
log_PDK1 | -0.27 | 0.34 | log_PDK1 | 0.17 | 0.68 | log_LDHA | -0.68 | 0.10 |
log_PDP1 | -0.51 | 0.09 | log_PDP1 | -0.28 | 0.44 | log_LDHA | -0.40 | 0.31 |
log_HIF1A | 0.18 | 0.50 | log_HIF1A | 0.48 | 0.20 | log_LDHA | -0.76 | 0.05 |
log_HIF1B | -0.26 | 0.32 | log_HIF1B | 0.11 | 0.76 | log_LDHA | -0.65 | 0.12 |
log_HIF2A | -0.21 | 0.45 | log_HIF2A | 0.30 | 0.47 | log_LDHA | -0.69 | 0.07 |
log_HIF3A | 0.29 | 0.28 | log_HIF3A | 0.45 | 0.20 | log_LDHA | -0.77 | 0.08 |
log_POK2 | -0.33 | 0.24 | log_POK2 | -0.16 | 0.64 | log_LDHA | -0.52 | 0.14 |
log_PDP2 | -0.41 | 0.17 | log_PDP2 | -0.01 | 0.99 | log_LDHA | -0.57 | 0.25 |
log_PDK3 | -0.30 | 0.27 | log_PDK3 | 0.00 | 1.00 | log_LDHA | -0.58 | 0.14 |
log_PDK4 | -0.32 | 0.27 | log_PDK4 | -0.37 | 0.31 | log_LDHA | -0.61 | 0.09 |
log_PDHE1A1 | -0.27 | 0.31 | log_PDHE1A1 | 0.68 | 0.24 | log_LDHA | -1.20 | 0.07 |
log_GADPH | 0.12 | 0.67 | log_GADPH | 0.40 | 0.34 | log_LDHA | -0.84 | 0.08 |
log_EPOR | 0.33 | 0.25 | log_EPOR | 1.14 | 0.08 | log_LDHA | -1.21 | 0.03 |
log_GLUT1 | missing | |||||||
log_LDHA | -0.58 | 0.09 | ||||||
log_CATD | -0.46 | 0.13 | log_CATD | -0.09 | 0.85 | log_LDHA | -0.51 | 0.30 |