Table 1 Seven auxological referral criteria taken from the Dutch Consensus Guideline [3].

Absolute height

HSDS* < -2.5

1

Clinical symptoms

HSDS* < -1.3 AND (dysmorphic features OR disproportions)

2

Persistent short stature after born SGA**

SGA** AND HSDS* < -1.88 after the age of 2 years

3

Short for target height and population (HSDScorr)

♂: < 10 yr and > 13.4 yr;

HSDS* < -1.3 AND HSDS-THSDS^§ < -1.3

4

♀: < 9 yr and > 12.3 yr

Pubertal age^‡:

♂: 10 – 13.4 yr;

♀: 9 – 12.3 yr

HSDS* < -1.3 AND HSDS-THSDS^§ < -1.3 AND pubertal signs (♂: genit ≥ Tanner stage 2 OR testis volume ≥ 4 ml; ♀: breast ≥ Tanner stage 2)

5

Height deflection^†

♂: < 10 yr and > 13.4 yr; ♀: < 9 yr and > 12.3 yr

T2 – T1 > 1

(SDS1 – SDS2)/(T2-T1) < -0.25 OR (SDS1 – SDS2) < -1

6

Pubertal age^‡:

♂: 10 – 13.4 yr; ♀:

9 – 12.3 yr

T2 – T1 > 1

(SDS1 – SDS2)/(T2-T1) < -0.25 OR (SDS1 – SDS2) < -1 With pubertal signs

7