Number of included trials | Number of participants | Adverse event | Relative risk (95% CI) |
---|---|---|---|
4 [10,11,21,25] | 526 | Sinus bradycardia | 7.42 (2.52, 21.87) Number needed to harm: 13 (95% CI: 8, 20) |
3 [10,11,21] | 464 | Arrhythmia requiring treatment | 1.04 (0.07, 16.39) |
4 [10,11,21,24] | 483 | Hypotension | 1.17 (0.96, 1.42) |
3 [10,21,25] | 318 | Thrombocytopenia | 1.47 (1.07, 2.03) Number needed to harm: 8 (95% CI: 5, 50) |
3 [10,11,25] | 500 | Coagulopathy | 1.28 (0.94, 1.75) |
2 [10,25] | 292 | Anemia | 1.75 (0.86, 3.57) |
3 [10,11,21] | 464 | Hypoglycemia | 0.76 (0.49 to 1.17) |
5 [10,11,21,24,25] | 545 | Abnormal renal function | 0.91 (0.79 to 1.05) |
2 [10,11] | 448 | Hepatic dysfunction | 0.83 (0.64, 1.09) |
4 [10,11,21,25] | 526 | Sepsis | 1.04 (0.45 to 2.39) |
5 [10,11,21,24,25] | 545 | Seizures | 1.04 (0.91 to 1.18) |
2 [10,25] | 292 | Hypokalemia | 1.02 (0.84 to 1.25) |