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Table 4 Rates of major neurodevelopmental impairment* detectable at 1 year adjusted age in Epochs 1 and 2.

From: Survival and major neurodevelopmental impairment in extremely low gestational age newborns born 1990–2000: a retrospective cohort study

 

Epoch 1

Epoch 2

 

# seen/# survivors (%)

% impaired (95% CI)

# seen/# survivors (%)

% impaired (95% CI)

23 weeks

4/4 (100)

0 (0, 60)

11/13 (85)

73 (39, 94)

24 weeks

22/22 (100)

41 (21, 64)

39/43 (91)

26 (13, 42)

25 weeks

41/43 (95)

15 (6, 29)

36/40 (90)

6 (1, 19)

26 weeks

63/68 (93)

22 (13, 34)

63/75 (85)

11 (5, 22)

27 weeks

57/70 (80)

16 (7, 28)

65/80 (81)

6 (2, 15)

23–27 weeks

187/207 (90)

20 (15, 27)

214/251 (85)

14 (10, 20)

  1. * Major neurodevelopmental impairment in infants seen in our follow up clinic: cerebral palsy, Bayley Scales of Infant Development Mental Development Index >2 SD below the mean, or blindness