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Table 4 Changes in illness severity and outcomes over time in infants <1000 g

From: Increasing illness severity in very low birth weight infants over a 9-year period

Infants <1000 g Cohort 1 1993–1996, n = 165 Cohort 2 1996–1999, n = 199 Cohort 3 1999–2002, n = 246
T4 (μg/dl) 5.4 ± 2.9 5.3 ± 3.1 4.7 ± 3.3 *
SNAP NA 15.3 ± 7.4 18.3 ± 8.9 †
Death 30% 27% 33%
Severe IVH 16% 14% 23% †
Death/Severe IVH 35% 36% 46% * †
  1. *p < .05, Cohort 1v 3
  2. ‡p < .05, Cohort 1 vs 2
  3. †p < .05, Cohort 2 vs 3