Table 1 Subject characteristics and main outcome.
TOTAL | RECTAL (15 MG/KG) | ORAL (15 MG/KG) | RECTAL (35 MG/KG) | |
|---|---|---|---|---|
Total | 51 | 18 | 16 | 17 |
Male Gender | ||||
N (%) | 29 (56.9) | 11 | 8 | 10 |
Age (years): | ||||
Mean (SD) | 4.1 (3.5) | 3.8 (2.8) | 4.0 (3.6) | 3.5 (3.0) |
Range | 0.5–13.1 | 0.6–13.1 | 0.5–10.2 | 0.5–12.4 |
Diagnosis:¶ N (%) | ||||
Pneumonia | 10 (19.6) | 3 | 2 | 5 |
UTI | 7 (13.7) | 2 | 4 | 1 |
Virus | 17 (33.3) | 6 | 4 | 7 |
Bacteremia | 5 (9.8) | 2 | 2 | 1 |
Others | 36 (70.5) | 15 | 12 | 9 |
Previous antipyretic | ||||
N (%) | ||||
Acetaminophen | 40(78.4) | 15 | 14 | 11 |
Ibuprofen | 8(15.6) | 2 | 2 | 4 |
Antibiotic intake | ||||
N (%) | 35 (68.6) | 16 | 8 | 11 |
Acetaminophen Dose (mg/kg): | ||||
Mean (SD) § | 14.1(2.3) | 15.0(0.0) | 31.7(6.7) | |
Range | 10.7–18.5 | 15.0–15.0 | 12.5–43.4 | |
Duration of fever (days): | ||||
Median | 3.0 | 3 | 1.3 | 5 |
Range | 0.5–101.0 | 1.0–90.0 | 0.5–15.0 | 1.0–101.0 |
Baseline temperature | ||||
Mean (SD) | 39.2 (0.7) | 39.1 (0.9) | 39.3 (0.6) | 39.1 (0.6) |
Time to max AP in hr: | ||||
Mean | 3.6 | 3.3 | 3.6 | 3.9 |
95% CI | 3.2–4.0 | 2.4–4.2 | 2.8–4.3 | 3.3–4.6 |