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Table 5 Association between congenital toxoplasmosis and developmental outcomes: multivariable analyses

From: Association between congenital toxoplasmosis and parent-reported developmental outcomes, concerns, and impairments, in 3 year old children

  Developmental outcome (Odds ratio and 95% confidence interval)
  PARENT COMPLETED
  Motor Speech & language Behaviour Cognition
All centres (N = 705) 1.30 (0.75, 2.25)2 1.10 (0.60, 2.02) 3,4 1.05 (0.66, 1.67) 2 0.85 (0.35, 2.09)
Sensitivity analyses
a) France only (N = 379)1 1.22 (0.61, 2.42)2 0.98 (0.45,2.14) 1.15 (0.64, 2.09) 0.55 (0.17, 1.76)2
b) Poland only (N = 134) 1.10 (0.30, 4.06) 0.54 (0.13, 2.26) 0.94 (0.30, 2.92) 1.02 (0.16, 6.62)
c) Children aged 36 to <41 months (N = 553) 1.18 (0.68, 2.05) 1.04 (0.54, 2.00) 1.25 (0.70, 2.22) 0.61 (0.25, 1.50)
d) Children with no signs before 4 months (N = 538 Poland excluded) 1.08 (0.57, 2.07) 1.10 (0.51, 2.36) 1.02 (0.57, 1.82)2 0.35 (0.10, 1.24)
  CHILD COMPLETED
  'Draw a Man' Line, circle, cross
All centres (N = 705) 1.27 (0.66, 2.44)5 1.13 (0.56, 2.25)
Sensitivity analyses
a) France only (N = 379)1 0.77 (0.35, 1.67) 0.93 (0.40, 2.18)
b) Poland only (N = 134) 1.00 (0.17, 5.77) 0.76 (0.13, 4.41)
c) Children aged 36 to <41 months (N = 553) 0.79 (0.39, 1.63)5 0.96 (0.48, 1.95)
d) Children with no signs before 4 months (N = 538 Poland excluded) 0.96 (0.46, 2.02) 1.03 (0.45, 2.36)
  1. All models include centre, maternal education, and child's age at completion of questionnaire
  2. 1adjusts for variability among centres relative to Lyon
  3. 2adjusted for maternal age
  4. 3adjusted for born outside the country
  5. 4adjusted for maternal age
  6. 5adjusted for gender, and maternal age squared