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Table 4 Changes in respiratory indices at PCW and at PC20-FEV1. The results are expressed as mean ± SD. (n = 35/36, as one child did not respond to MCH and his spirometry did not change throughout the test).

From: Methacholine bronchial provocation measured by spirometry versus wheeze detection in preschool children

Parameter End of test PC20-FEV1
FVC - 41.3 ± 15.5 - 18.4 ± 10.0 *
FEV1 - 44.7 ± 14.5 - 24.6 ± 6.4 *
FEV1/FVC - 6.09 ± 6.8 - 4.1 ± 3.8 *
PEFR - 44.2 ± 13.2 - 21.4 ± 10.6 *
FEF50 - 61.2 ± 14.2 - 38.6 ± 16.9 *
Expiratory time (sec) +2.8 ± 0.4 +2.2 ± 0.4 *
  1. * Changes at PC20-FEV1 are significantly lower than at "end of test", p < 0.01