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Table 5 Effect of ACE genotype on Outcomes in African-American Infants

From: The Angiotensin Converting Enzyme Insertion/Deletion polymorphism is not associated with an increased risk of death or bronchopulmonary dysplasia in ventilated very low birth weight infants

 

ACE Genotype

 

II (n = 39)

ID (n = 88)

DD (n = 66)

P value

Oxygen at 28 days

24/36 (67)

57/82 (70)

43/59 (73)

0.805

Oxygen at 36 weeks PCA

7/34 (21)

22/79 (28)

16/58 (28)

0.698

Death <28 days

3 (8)

6 (7)

8 (12)

0.517

Death or Oxygen at 36 weeks

12 (31)

31 (35)

25 (37)

0.792

Death ≥ 28 days

3 (8)

7 (9)

4 (7)

0.925

IVHa

14/38 (37)

23/86 (27)

25/67 (37)

0.311

IVH ≥ Grade 3a

7/38 (18)

15/86 (17)

17/67 (25)

0.438

PVLa

1/38 (3)

5/86 (6)

8 (12)

0.145

  1. Numbers in parenthesis represent percentages.
  2. aNot all infants had cranial US evaluations
  3. PCA Postconceptional age IVH Intraventricular Hemorrhage PVL Periventricular leukomalacia
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BMC Pediatrics

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