Lactobacillus caseistrain GG in the treatment of infants with acute watery diarrhea: A randomized, double-blind, placebo controlled clinical trial [ISRCTN67363048]

Table 3 Clinical outcomes

	Placebo group	N	LGG group	N	P	Difference between means
Discharge condition		89		90
Early withdrawal	11 (12.4%)		8 (8.9%)		0.609
Treatment failure	16 (18.0%)		19 (21.1%)		0.734
Cessation of diarrhea	51 (57.3%)		52 (57.8%)		0.931
Unresolved diarrhea	11 (12.45%)		11 (12.2%)		0.842
Mean duration of diarrhea (hours)*	50.4 ± 28.0	51	58.5 ± 30.2	52	0.157	-19.6 to 3.4
Mean duration of hospitalization (hours)**	74.7 ± 33.7	62	81.2 ± 32.6	63	0.280	-18.4 to 5.4
Total stool output (ml/kg)	195.0 ± 171.9	89	247.8 ± 180.2	90	0.047	-105.4 to -0.2
Total oral rehydration solution intake (ml/kg)	236.5 ± 195.6	89	272.8 ± 188.1	90	0.208	-93.7 to 21.1
Total study formula intake (ml/kg)	215.5 ± 136.3	89	231.5 ± 136.6	90	0.435	-56.8 to 24.8
Total energy intake (Kcal/kg)^§	220.7 ± 140.4	89	247.4 ± 143.0	90	0.209	-69.1 to 15.7
Total volume of vomitus (ml/kg)	27.6 ± 45.5	89	27.4 ± 33.9	90	0.968	-11.8 to 12.2
Total volume of urine (ml/kg)	81.5 ± 65.2	89	87.1 ± 69.4	90	0.579	-25.7 to 14.5

* For patients who ceased diarrhea before 120 hours.
** Patients with treatment failure or early withdrawals are excluded.
^§ Calculated from calories provided by study formula, soft foods, breastmilk, and oral rehydration solution.
Values are mean ± SD, n (%), or 95% confidence limits.

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