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Table 3 Clinical outcomes

From: Lactobacillus caseistrain GG in the treatment of infants with acute watery diarrhea: A randomized, double-blind, placebo controlled clinical trial [ISRCTN67363048]

  Placebo group N LGG group N P Difference between means
Discharge condition   89   90   
   Early withdrawal 11 (12.4%)   8 (8.9%)   0.609  
   Treatment failure 16 (18.0%)   19 (21.1%)   0.734  
   Cessation of diarrhea 51 (57.3%)   52 (57.8%)   0.931  
   Unresolved diarrhea 11 (12.45%)   11 (12.2%)   0.842  
Mean duration of diarrhea (hours)* 50.4 ± 28.0 51 58.5 ± 30.2 52 0.157 -19.6 to 3.4
Mean duration of hospitalization (hours)** 74.7 ± 33.7 62 81.2 ± 32.6 63 0.280 -18.4 to 5.4
Total stool output (ml/kg) 195.0 ± 171.9 89 247.8 ± 180.2 90 0.047 -105.4 to -0.2
Total oral rehydration solution intake (ml/kg) 236.5 ± 195.6 89 272.8 ± 188.1 90 0.208 -93.7 to 21.1
Total study formula intake (ml/kg) 215.5 ± 136.3 89 231.5 ± 136.6 90 0.435 -56.8 to 24.8
Total energy intake (Kcal/kg)§ 220.7 ± 140.4 89 247.4 ± 143.0 90 0.209 -69.1 to 15.7
Total volume of vomitus (ml/kg) 27.6 ± 45.5 89 27.4 ± 33.9 90 0.968 -11.8 to 12.2
Total volume of urine (ml/kg) 81.5 ± 65.2 89 87.1 ± 69.4 90 0.579 -25.7 to 14.5
  1. * For patients who ceased diarrhea before 120 hours.
  2. ** Patients with treatment failure or early withdrawals are excluded.
  3. § Calculated from calories provided by study formula, soft foods, breastmilk, and oral rehydration solution.
  4. Values are mean ± SD, n (%), or 95% confidence limits.