Table 2 Biochemical markers of oxidative stress in enrolled newborns
S. No. | Biochemical Markers | Study Group (n = 20) | Control Group (n = 20) | P-value* | Mean difference (95% CI) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Mean (SD) | SE | Median | Range | Mean (SD) | SE | Median | Range | ||||
1. | Malondialdehyde (nmol/mL) | 5.33 (0.72) | 0.16 | 5.23 | 4.21–6.37 | 2.55 (0.22) | 0.05 | 2.51 | 2.12–2.92 | <0.0001 | 2.78 (2.43, 3.13) |
2. | Superoxide dismutase (U/g Hb) | 493.57 (54.91) | 12.28 | 493.53 | 402.4–583.5 | 786.81 (79.05) | 17.68 | 752.25 | 692.4–956.4 | <0.0001 | -293.23 (-336.80, -249.66) |
3. | Catalase (U/g Hb) | 1.48 (0.24) | 0.05 | 1.45 | 1.09–2.02 | 2.31 (0.20) | 0.04 | 2.28 | 2.01–2.72 | <0.0001 | -0.82 (-0.97, -0.68) |
4. | Reduced glutathione (μ mol/g Hb) | 2.84 (0.37) | 0.08 | 2.85 | 2.31–3.41 | 6.42 (0.23) | 0.05 | 6.35 | 6.01–6.82 | <0.0001 | -3.58 (-3.78, -3.38) |