Table 1 Clinical findings in 61 infants with congenital and perinatal infection and specific IgM antibodies to Cytomegalovirus detected by enzymoimmunoassay
From: Human Cytomegalovirus: detection of congenital and perinatal infection in Argentina
Congenital | |||
|---|---|---|---|
Patient No | Age (day/month) | IgM | Clinical and Laboratory data |
1 | 5 d | + | IUGR, cerebral calcifications. |
2 | 21 d | - | Ascites, renal problems, elevated liver enzymes. |
3 | 6 d | + | SGA, purpura, hepatosplenomegaly |
4, 8, 29 | 5 d, 5 d, 28 d | -, +, + | SGA |
5 | 18 d | + | Petechiae, hepatosplenomegaly, jaundice |
6, 14., 32 | 5 d, 8 d, 8 d | +, +, + | Hepatosplenomegaly, cerebral calcifications |
7 | 14 d | + | Sepsis, thrombocytopenia. |
9 | 20 m | - | AWGA, purpura, elevated liver enzymes. |
10 | 5 d | + | SGA, cerebral microcalcifications, microcephaly |
11 | 5 d | - | SGA, purpura, hepatosplenomegaly, thrombocytopenia |
12 | 4 d | - | AWGA, purpura, elevated liver enzymes, trombocytopenia. |
13 | 11 d | + | Sepsis, petechiae, thrombocytopenia |
15, 21, 33 | 5 d, 5 d, 5 d | -, +, - | SGA, purpura, HIV+. |
16 | 6 d | - | Cerebral calcifications, thrombocytopenia, HIV+ mother. |
17 | 5 d | + | Foetal dystrophy, inclusion-bearing cells in urine. |
18 | 14 d | S/s | IUGR, sepsis, foetal dystrophy |
19 | 8 d | + | Hepatosplenomegaly, sepsis, died of hepatic failure |
20 | 18 d | + | SGA, hydrocephalus, respiratory problems |
22 | 3 m | S/s | Cerebral calcifications, congenital toxoplasmosis |
23 | 24 d | - | Cholestasis, purpura, cerebral calcifications, elevated liver enzymes, sepsis. |
24 | 5 d | - | Microcephaly, cerebral calcifications (irregular and punctate), thrombocytopenia |
25 | 5 d | + | AWGA, hepatosplenomegaly, sepsis, jaundice. |
26 | 3 m | - | Chorioretinitis |
27 | 5 d | - | SGA, hepatosplenomegaly, petechiae, anaemia, cholestasis |
28 | 5 d | + | SGA, purpura, cerebral calcifications, thrombocytopenia, splenomegaly, elevated liver enzymes |
30 | 5 d | + | Hepatosplenomegaly, purpura |
31 | 5 m | - | RNPT, AWGA, seizures, maturational delay, palsy at age one year |
Perinatal | |||
39 | 40 d | - | SGA, petechiae, hepatomegaly, respiratory problems. |
41 | 5 m | + | HIV+, cerebral calcifications, hepatosplenomegaly, anaemia |
47 | 34 d | + | Neonatal jaundice |
50 | 8 m | - | SGA, Hepatosplenomegaly, elevated liver enzymes, anaemia, jaundice at age 2 months |
Congenital or Perinatal | |||
34, 37, 48 | 3 m, 8 m, 7 m | -, -, S/s | Hepatosplenomegaly, HIV+ |
35 | 4 m | + | Jaundice, biliary atresia |
36 | 63 d | + | Anaemia, hepatosplenomegaly, malnutrition, hyperbilirubinemia |
38, 43 | 4 m, 3 m | -, - | Petechiae, hyperbilirubinemia, splenomegaly |
40 | 40 d | - | Ascitis, renal problems, elevated liver enzymes |
42 | 42 d | S/s | SGA |
44 | 3 m | + | Premature, scanty maternal contact |
45 | 24 m | - | Malnutrition, pancytopenia. |
46 | 12 m | + | Aplastic crisis |
49 | 4 m | + | SGA, hepatosplenomegaly, jaundice, anaemia, petechiae. |
51 | 2 m | + | Sepsis, cyanosis, vomiting |
52 | 1 m | S/s | Petechiae, jaundice, anaemia, hepatosplenomegaly |
53 | 5 m | + | Mental retardation, anaemia |
54 | 2 m | - | RNPT, SGA, IUGR, anaemia, microcephaly, tricuspid valve insufficiency |
55 | 3 m | - | SGA, rash, fever spikes |
56, 58 | 5 m, 33 d | -, - | SGA, respiratory problems. |
57 | 34 d | + | IUGR, sepsis, hepatomegaly, oesophageal atresia, elevated liver enzymes |
59 | 26 d | - | SGA, HIV+ mother |
60 | 38 d | + | IUGR, microcephaly, jaundice |
61 | 6 m | - | Normal at birth, neutropenia |