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Table 3 Univariate and multivariate logistic regression analyses of variables potentially associated with in-hospital mortality

From: Effectiveness of predicting in-hospital mortality in critically ill children by assessing blood lactate levels at admission

 

Univariate binary logistic regression

Multivariate logistic regression

OR (95% CI)

P value

OR (95% CI)

P value

Age

1.02 (0.96-1.08)

0.542

1.06 (0.96-1.16)

0.249

Gender

1.58 (1.07-2.33)

0.021

1.11 (0.63-1.97)

0.715

PRISM III score

1.18 (1.15-1.21)

<0.001

1.15 (1.11-1.20)

<0.001e

Laboratory findings on admission dayf

Lactate

1.38 (1.30-1.46)

<0.001a

1.17 (1.07-1.29)

0.001b,c

Albumin

0.86 (0.83-0.89)

<0.001

0.92 (0.88-0.96)

<0.001d

Glucose

1.11 (1.08-1.13)

<0.001

1.00 (0.96-1.03)

0.829

Creatinine

1.01 (1.00-1.01)

<0.001

0.99 (0.98-1.01)

0.428

Urea nitrogen

1.05 (1.01-1.08)

0.006

1.03 (0.94-1.12)

0.556

Total bilirubin

1.01 (1.00-1.01)

0.010

1.01 (0.99-1.01)

0.080

Bicarbonate

0.89 (0.87-0.93)

<0.001

1.03 (0.98-1.08)

0.217

Arterial pH

0.01 (0.00-0.03)

<0.001

0.54 (0.06-4.75)

0.580

  1. CI, confidence interval; OR, odds ratio; PRISM III, pediatric risk of mortality III.
  2. The p value of the Hosmer-Lemeshow goodness-of-fit test for the multivariate logistic regression model was 0.611.
  3. aThe association of blood lactate with in-hospital mortality remained significant after adjustment for age, gender, and the PRISM III score (OR = 1.27; 95% CI, 1.19-1.35; p <0.001). bThe association of the blood lactate level with in-hospital mortality remained significant after adjustment for serum albumin and the PRISM score (OR = 1.17; 95% CI, 1.09-1.26; p <0.001). cOdds ratio represents the increase in risk per 1 mmom/l increase in lactate concentration. dOdds ratio per 1 g/l increase in albumin level. eOdds ratio per 1-point increase in PRISM III score. fThe first available laboratory values during the first 24 hours after admission.