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Table 2 Comparison of demographic and clinical characteristics and laboratory findings on admission day among children with different concentrations of blood lactate

From: Effectiveness of predicting in-hospital mortality in critically ill children by assessing blood lactate levels at admission

Admission blood lactate, mmom/l

0.0-2.0

2.1-4.0

4.1-6.0

6.1-8.0

8.1-10.0

>10.0

P value

n

250

485

204

79

34

57

 

Age, years

1.75 [0.58-4.00]

1.00 [0.33-3.00]

0.67 [0.25-2.00]

0.54 [0.25-3.50]

0.42 [0.17-1.25]

0.92 [0.33-3.00]

<0.001

Gender, male/female

163/87

304/181

122/82

60/19

9/25

31/26

<0.001

PRISM III score

3 [0–6]

3 [0–6]

3 [0.75-7]

5 [2–11]

8 [4–15.75]

14 [6–24]

<0.001

MODS ≥3a, n

11 (4.4)

24 (4.9)

20 (9.8)

20 (25.3)

12 (35.3)

34 (59.6)

<0.001

Mechanical ventilationb, n

29 (11.6)

95 (19.6)

48 (23.5)

23 (29.1)

13 (38.2)

31 (54.4)

<0.001

In-hospital mortality, n

7 (2.8)

27 (5.6)

18 (8.8)

14 (17.7)

9 (26.5)

40 (70.2)

<0.001

Laboratory findings on admission dayc

Albumin, g/l

42.6

42.7

42.0

40.2

39.6

32.8

<0.001

[39.1-45.8]

[39.8-46.0]

[39.9-45.7]

[34.2-44.5]

[35.9-43.15]

[29.0-40.0]

Glucose, mmol/l

6.50

6.90

7.60

8.90

11.35

16.27

<0.001

[5.35-8.00]

[5.70-9.00]

[6.15-11.37]

[6.65-14.02]

[7.40-21.21]

[10.78-27.90]

Creatinine, μmol/l

28.2

27.4

27.8

31.7

37.6

62.4

<0.001

[23.2-35.5]

[23.2-35.0]

[23.1-37.5]

[22.8-48.8]

[25.9-60.1]

[43.0-79.7]

BUN, μmol/l

3.64

3.70

3.59

4.46

4.87

4.72

<0.001

[2.62-5.04]

[2.62-4.92]

[2.35-5.12]

[2.85-6.69]

[3.04-6.48]

[3.80-6.92]

Total bilirubin, μmol/l

6.08

6.50

7.01

9.43

4.91

6.71

<0.001

[4.20-8.50]

[4.21-9.73]

[4.73-11.69]

[6.18-17.28]

[3.33-8.89]

[4.03-12.61]

Bicarbonate, μmol/l

21.4

20.8

20.8

17.7

15.9

11.5

<0.001

[18.8-24.4]

[18.4-24.0]

[17.9-23.8]

[14.8-21.4]

[11.7-20.4]

[6.6-15.3]

Arterial pH

7.439

7.421

7.390

7.368

7.267

7.177

<0.001

[7.385-7.488]

[7.364-7.476]

[7.332-7.456]

[7.304-7.464]

[7.141-7.338]

[7.005-7.272]

  1. Values are median [interquartile range]. Numbers in parentheses denote percentages.
  2. BUN, blood urea nitrogen; MODS, multi-organ dysfunction syndrome; PRISM III, pediatric risk of mortality III.
  3. aMODS developed during hospitalization. bAdministration during hospitalization. cThe first available laboratory values during the first 24 hours after admission.