Table 2 Associations between CYP19A1 and PPARG methylation (%) and age at pubertal development.
From: CYP19A1 promoter methylation in saliva associated with milestones of pubertal timing in urban girls
| Â | Unadjusted model | Adjusted model* | ||||
|---|---|---|---|---|---|---|
| Â | N | HR (95% CI) | p value | N | HR (95% CI) | p value |
Pubic Hair (PH2) development | ||||||
CYP19A1 | 125 | 0.95 (0.90 - 0.99) | 0.04 | 120 | 0.95 (0.90 - 1.00) | 0.05 |
PPARG | 129 | 0.99 (0.90 - 1.08) | 0.75 | 124 | 0.96 (0.87 - 1.05) | 0.37 |
Breast development (B2) | ||||||
CYP19A1 | 125 | 0.97 (0.92 - 1.02) | 0.17 | 120 | 0.96 (0.91 - 1.01) | 0.11 |
PPARG | 129 | 1.04 (0.96 - 1.13) | 0.32 | 124 | 1.03 (0.94 - 1.12) | 0.54 |