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Table 4 Laboratory factors for IVIG resistance in children with Kawasaki disease

From: Hepatobiliary risk factors for clinical outcome of Kawasaki disease in children

Variables

IVIG response

IVIG resistance

Pvalue

(n = 47)

(n = 17)

WBC (/mm3)

13,990 (4,000 ~ 28,000)

18,710 (7,460 ~ 30,300)

0.323

Neutrophils (%)

79.1 (29.3 ~ 95.2)

83.9 (63.6 ~ 95.3)

0.342

Hemoglobin (g/dL)

11.6 (9.2 ~ 14.8)

12.2 (8.7 ~ 14.3)

0.460

Platelet count (/mm3)

323,000 (64,000 ~ 573,000)

287,000 (94,000 ~ 513,000)

0.861

Albumin (g/dL)

3.8 (2.6 ~ 4.4)

3.7 (3.0 ~ 4.6)

0.801

Total bilirubin (mg/dL)

1.7 (0.2 ~ 5.7)

2.5 (0.6 ~ 4.7)

0.164

Direct bilirubin (mg/dL)

2.1 (0.1 ~ 5.3)

2.2 (1.8 ~ 4.1)

0.595

AST (IU/L)

128 (19 ~ 1,287)

88 (34 ~ 646)

0.837

ALT (IU/L)

172 (6 ~ 1,076)

168 (18 ~ 1,027)

0.677

γGT (IU/L)

227.5 (20 ~ 577)

160.0 (105 ~ 258)

0.365

ESR (mm/h)

38 (3 ~ 120)

47 (30 ~ 72)

0.499

CRP (mg/dL)

8.3 (0.2 ~ 26.0)

10.9 (4.7 ~ 26.0)

0.354

PT INR

1.2 (1.0 ~ 10.9)

1.33 (1.1 ~ 1.5)

0.024*

aPTT (sec)

44.2 (26.8 ~ 58.7)

45.0 (41.8 ~ 55.0)

0.682

  1. Data are presented as median (range).
  2. *p < 0.05.
  3. aPTT, activated partial thromboplastin time; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CI, confidence interval; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; γGT, gamma glutamyl transferase, INR, international normalized ratio; PT, prothrombin time; WBC, white blood cell.