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Table 3 Previous reports of skin involvement in APS 1 patients

From: Cutaneous vasculitis in patients with autoimmune polyendocrine syndrome type 1: report of a case and brief review of the literature

Author and year of publication N. of cases Age at the onset of skin lesions (yrs) Aspect of skin lesions First typical component, age at onset (yrs) Biopsy
Case series      
Craig JM et al. 1955 [7] 1/3 2.8 erythema marginatum/recurrent skin rash CMC, 3 increased melanin content
Betterle C et al. 1998 [2] 1/41 n.a. n.a. n.a. n.a.
Perheentupa J 2006 [3] 13/91 0.7–31 fleeting maculopapular, morbilliform, or urticarial rash n.a 2/4 biopsies revealed vasculitis
Trebušak Podkrajšek K et al. 2008 [6] 1/11 2 n.a. HPT, 7.5 n.a.
Posovszky C et al. 2012 [15] 2/13 1 n.a. CMC, 2.0 n.a
5 chronic recurrent urticaria CMC, 3.0
Case reports      
Quinto MG et al. 1964 [8] 1 0.9 multiform erythema HPT + CMC, 4.0 n.a.
Stickler GB et al. 1965 [9] 1 7.6 evanescent trunkal macular rash HPT + CMC, 9.1 n.a.
Spörkmann K-H et al. 1990 [10] 1 1.2 multiform erythema HPT, 3.0 n.a.
Garty B 1998 [11] 1 22 erythema annulare centrifugum HPT, 5 lymphohistiocytic vasculitis
Füchtenbusch M et al. 2003 [12] 1 31 purpuric subepidermal nodules progressing in deep cutaneous ulcers HPT, 3.0 panniculitis and lymphocytic vasculitis
Kapelari K et al. 2004 [13] 1 16 photosensitive facial rash (diagnosis of systemic lupus erythematosus) n.a. n.a.
Hoorweg-Nijman G et al. 2008 [14] 1 1.2 n.a. HPT, 9.0 n.a.
Montin D et al. 2008 [16] 2 1.1 urticarial rash (vasculitic rash) CMC, 1.5 n.a.
7 urticarial rash CMC, 7.0
Rodríguez Sánchez De La Blanca A et al. 2012 [18] 1 6 photosensitive rash HPT, 9.0 n.a.
O’ Gorman CS et al. 2013 [17] 1 1 intermittent urticarial rash HPT + CMC, 1 lymphocytic vasculitis
  1. CMC: chronic mucocutaneous candidiasias; HPT: chronic idiopathic hypoparathyroidism; n.a.: not available.