Table 1 Comparative alignment of the amino acid sequence of BTK

Human

ENST00000308731

373

H Q H N S A G L I S R L K Y P V S Q Q N K N A

Mutated

-

373

H Q H N S A G L I S R V K Y P V S Q Q N K N A

Ptroglodytes

ENSPTRG00000022104

373

H Q H N S A G L I S R L K Y P V S Q Q N K N A

Mmulatta

ENSMMUG00000019573

373

H Q H N S A G L I S R L K Y P V S Q Q N K N A

Mmusculus

ENSMUSG00000031264

373

H Q H N S A G L I S R L K Y P V S K Q N K N A

Ggallus

ENSGALG00000004958

371

H Q H N S A G L I S R L K Y P V S R H Q K S A

Trubripes

ENSTRUG00000012144

356

H Q H N A A G M V S R L K Y I V T T R M R

Drerio

ENSDARG00000004433

352

H Q H N A A G L V S R L K Y I V S N R A Q N A

Fcatus

ENSFCAG00000015395

373

X X X X X X X L I S R L K Y P V S Q Q N K N A

Xtropicalis

ENSXETG00000018152

364

H Q H N A A G L I S R L K Y P V C S L R K T A