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Table 1 Characteristics of treatment protocols

From: Final height and body mass index in adult survivors of childhood acute lymphoblastic leukemia treated without cranial radiotherapy: a retrospective longitudinal multicenter Italian study

Protocols

87

8801

8802

8805

9101

9102

9501 – 9502 armA

9502 armB

2000

PDN

2500

1830

1830

150

2030

1970

1970

1620

1910

VCR

20.5

9

12

9

12

12

12

15

18

DNM

180

160

160

-

120

120

-

120

120

MTX IT

Ù§

Ù§

Ù§

Ù§

Ù§

Ù§

Ù§

Ù§

Ù§

L-ASP

5400

80000

80000

-

80000

80000

120000

120000

80000

6-MP

6000

29920

25900

-

5100

28920

27350

6710

6830

MTX IV

180

1540

1500

30

1488

1500

1488

1500

1500

CPM

-

2000

3000

1600

1000

3000

1000

3000

2500

DESA

-

189

249

300

249

249

261

297

409

6-TG

-

900

900

-

840

840

780

780

780

ARA-C

-

600

600

900

600

1800

600

1600

600-1800

IFO

-

-

-

12000

-

-

-

-

-

VM-26

-

-

-

600

-

-

-

-

-

ADM

-

60

120

150

120

120

120

120

60-120

Num. patients exposed

2

1

2

4

5

28

2

57

6

  1. Legend: Drugs are expressed as cumulative dose (mg/mq). PDN, prednisolone; VCR, vincristine; DNM, daunorubicin; MTX, metotrexate; IT, intrathecal; Ù§ included; L-ASP; L-asparaginase (UI/mq); 6-MP, 6-mercatopurine; IV, intravenously; CPM, cyclophosphamide; DESA, dexamethasone; 6-TG, 6-thioguanine; ARA-C, cytosine arabinoside.; IFO, ifosfamide; VM-26,teniposide; ADM, adriamycin.