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Table 2 Applicability and safety outcomes in infants randomised to receive surfactant via the Hobart method

From: The OPTIMIST-A trial: evaluation of minimally-invasive surfactant therapy in preterm infants 25–28 weeks gestation

Incidence of successful surfactant administration via MIST

Duration of hypoxaemia (SpO2 < 80%)

Number of catheterisation attempts

Requirement for, and duration of, positive pressure ventilation by mask

Duration of bradycardia (heart rate < 100 beats per minute)

Incidence of apparent discomfort