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Table 6 Prevalence of any suppurative OM in each age group, by vaccination group

From: Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules

 

PCV7 424*

PHiD-CV10 432*

Absolute risk difference [95%CI]

P value

Age group

n

%

n

%

3 to <6

4/8

50%

3/9

33%

−17% [−63 to 30]

0.48

6 to <9

34/47

71%

33/60

55%

−16% [−34 to 2]

0.09

9 to <12

27/38

71%

21/45

47%

−24% [−45 to −4]

0.03

12 to <18

50/84

59%

46/114

40%

−19% [−33 to −5]

0.008

18 to <24

54/98

55%

39/101

39%

−16% [−30 to −3]

0.02

24 to <36

48/148

32%

27/103

26%

−6% [−18 to 5]

0.29

  1. *Denominator: Dry perforation (8 children in the PCV7 group and 5 children in the PHiD-CV10 group) have been excluded.
  2. Any suppurative OM any AOMwoP (Acute Otitis Media without Perforation), any AOMwiP (Acute Otitis Media with Perforation), or any CSOM (Chronic Suppurative Otitis Media).
  3. CI, Confidence Interval.
  4. PCV7, 7-valent pneumococcal conjugate vaccine.
  5. PHiD-CV10, 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine.