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Table 6 Prevalence of any suppurative OM in each age group, by vaccination group

From: Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules

  PCV7 424* PHiD-CV10 432* Absolute risk difference [95%CI] P value
Age group n % n %
3 to <6 4/8 50% 3/9 33% −17% [−63 to 30] 0.48
6 to <9 34/47 71% 33/60 55% −16% [−34 to 2] 0.09
9 to <12 27/38 71% 21/45 47% −24% [−45 to −4] 0.03
12 to <18 50/84 59% 46/114 40% −19% [−33 to −5] 0.008
18 to <24 54/98 55% 39/101 39% −16% [−30 to −3] 0.02
24 to <36 48/148 32% 27/103 26% −6% [−18 to 5] 0.29
  1. *Denominator: Dry perforation (8 children in the PCV7 group and 5 children in the PHiD-CV10 group) have been excluded.
  2. Any suppurative OM any AOMwoP (Acute Otitis Media without Perforation), any AOMwiP (Acute Otitis Media with Perforation), or any CSOM (Chronic Suppurative Otitis Media).
  3. CI, Confidence Interval.
  4. PCV7, 7-valent pneumococcal conjugate vaccine.
  5. PHiD-CV10, 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine.