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Table 4 OM risk factors, by vaccination group

From: Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules

  PCV7 PHiD-CV10 Absolute difference in mean or % [95% CI] P*
  N Mean (SD) or % N Mean (SD) or %   
Risk factor questionnaire response
No parents consented 413/444 93% 296/451 66% −27% [−32 to −22] <0.0001
Mother interviewed 400/413 97% 290/296 98% 1% [−1 to 3] 0.36
Characteristics of children in consented subgroups
  PCV7 PHiD-CV10   
Age (months) 413 20 (8) 296 18(7) 2.0 [0.9 to 3.2] 0.0008
Sex (female) 198 48% 151 51% 3% [−4 to 11] 0.42
Any Suppurative OM 208/395 53% 104/285 36% −16% [−24 to −9] <0.0001
Risk factors
Crowding (persons per household) 402 8.6 (4.5) 290 8.2 (3.9) −0.4 [−1.0 to 0.3] 0.23
Crowding (children < 5 years of age per household) 408 2.4 (1.6) 291 2.1 (1.2) −0.3 [−0.5 to −0.1] 0.01
Crowding Index (%households with > 2 additional children < 5 years of age) 132/408 32% 75/291 26% −6% [−13 to 0.2] 0.06
Child Care (any attendance > 3 days per week) 51/409 12% 41/295 14% 1.4% [−4 to 7] 0.58
Child Care (days/week) 408 0.68 (1.7) 295 0.77 (1.7) 0.09 [−0.34 to 0.16] 0.49
Washed with soap yesterday 327/362 90% 258/293 88% −2% [−7 to 3] 0.35
Any sibling with history of “runny ears” 101/370 27% 80/249 32% 5% [−3 to 12] 0.20
Child near campfire last week 134/402 34% 88/287 31% −3% [−10 to 4] 0.46
Maternal smoking 233/410 57% 178/283 61% 4% [−3 to 11] 0.29
Maternal age at birth of this child 297 25 (5.4) 244 26 (6.4) 1 [0.1 to 2] 0.04
Maternal education (certificate) 105/382 27% 60/247 24% −3% [−10 to 4] 0.37
Never breast fed 28/409 7% 14/296 5% −2% [−6 to 1] 0.23
Pacifier (ever) 78/404 19% 52/296 18% −2% [−8 to 4] 0.56
  1. *Bold signifies P value less than 0.05.