Figure 1

Sequential MR studies in a newborn with severe HIE and a central pattern of injury (ID number 12). A. Early MR study. A.a. Axial diffusion-weighted image: restricted diffusion in the thalami; A.b. Axial T1 weighted images: abnormal high intensity within the basal ganglia and thalami (BGT) and loss of the normal intensity of the posterior limb of the internal capsule. A.c. Axial T2 weighted image. Low and high signal intensity within the basal ganglia and thalami. B. Late MRI study confirmed the previous findings. Sagittal (B.a.) and axial (B.b.) T1 weighted images showing an abnormal widespread high intensity of BGT and confirming the absence of the normal intensity of the posterior limb of the internal capsule. Cortical highlighting around central fissure. B.c. Axial T2 weighted images with heterogeneity of the signal in BGT more evident than in the early MRI.