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Table 3 Annual prescription rates per 1,000 person years of single antibiotic agents and combinations in 2008 (children and adolescents ≤18 years)

From: Systemic antibiotic prescribing to paediatric outpatients in 5 European countries: a population-based cohort study

Antibiotic agenta

Aarhus (DK)

Emilia Romagna (IT)

GePaRD (DE)

PHARMO (NL)

THIN (UK)

Tetracyclines

     

Doxycycline

0.2

1.2

10.6

11.9

6.3

Lymecycline

0.6

1.5

.

.

16.4

Oxytetracycline

<0.1

.

.

.

13.9

Minocycline

.

3.4

6.3

6.9

6.1

Penicillines

     

Amoxicillin

121.5

230.8

120.7

124.1

221.0

Pivmecillinam

17.6

.

.

.

<0.1

Phenoxymethylpenicillin

219.1

.

70.5

0.3

71.9

Pheneticillin

-

-

-

15.9

-

Dicloxacillin

29.4

.

<0.1

.

.

Flucloxacillin

0.1

<0.1

0.4

9.7

58.2

Amoxicillin plus enzyme inhibitor

7.3

318.0

11.0

37.6

23.3

Cephalosporines

     

Cefalexin

<0.1

0.7

1.2

<0.1

16.6

Cefadroxil

.

0.4

12.5

.

0.6

Cefuroxime

0.1

8.8

25.2

0.3

0.2

Cefaclor

.

27.9

81.2

0.2

5.0

Ceftriaxone

<0.1

9.8

0.2

0.1

<0.1

Cefixime

.

58.6

16.1

.

0.4

Cefpodoxime

.

43.5

16.0

.

<0.1

Ceftibuten

.

22.6

2.9

<0.1

.

Sulfonamides and Trimethoprim

     

Trimethoprim

2.9

.

4.1

5.5

32.0

Sulfamethizole

14.2

.

.

.

.

Sulfamethoxazole and trimethoprim

.

5.1

26.2

12.4

0.8

Macrolides

     

Erythromycin

27.0

1.6

36.8

4.0

56.8

Roxithromycin

7.1

3.2

16.1

0.1

.

Clarithromycin

5.4

96.7

26.5

16.9

8.5

Azithromycin

20.8

92.1

34.3

25.8

4.1

Nitrofuran derivatives

     

Nitrofurantoin

2.8

<0.1

2.1

17.0

2.3

Other antibacterials

     

Fosfomycin

.

9.2

0.6

0.2

.

Others

5.0

22.0

38.9

5.3

10.5

  1. aThe 12 most prescribed agents per database in 2008 were selected. Remaining agents were labelled as ‘others’.