Skip to main content

Table 3 Annual prescription rates per 1,000 person years of single antibiotic agents and combinations in 2008 (children and adolescents ≤18 years)

From: Systemic antibiotic prescribing to paediatric outpatients in 5 European countries: a population-based cohort study

Antibiotic agenta Aarhus (DK) Emilia Romagna (IT) GePaRD (DE) PHARMO (NL) THIN (UK)
Tetracyclines      
Doxycycline 0.2 1.2 10.6 11.9 6.3
Lymecycline 0.6 1.5 . . 16.4
Oxytetracycline <0.1 . . . 13.9
Minocycline . 3.4 6.3 6.9 6.1
Penicillines      
Amoxicillin 121.5 230.8 120.7 124.1 221.0
Pivmecillinam 17.6 . . . <0.1
Phenoxymethylpenicillin 219.1 . 70.5 0.3 71.9
Pheneticillin - - - 15.9 -
Dicloxacillin 29.4 . <0.1 . .
Flucloxacillin 0.1 <0.1 0.4 9.7 58.2
Amoxicillin plus enzyme inhibitor 7.3 318.0 11.0 37.6 23.3
Cephalosporines      
Cefalexin <0.1 0.7 1.2 <0.1 16.6
Cefadroxil . 0.4 12.5 . 0.6
Cefuroxime 0.1 8.8 25.2 0.3 0.2
Cefaclor . 27.9 81.2 0.2 5.0
Ceftriaxone <0.1 9.8 0.2 0.1 <0.1
Cefixime . 58.6 16.1 . 0.4
Cefpodoxime . 43.5 16.0 . <0.1
Ceftibuten . 22.6 2.9 <0.1 .
Sulfonamides and Trimethoprim      
Trimethoprim 2.9 . 4.1 5.5 32.0
Sulfamethizole 14.2 . . . .
Sulfamethoxazole and trimethoprim . 5.1 26.2 12.4 0.8
Macrolides      
Erythromycin 27.0 1.6 36.8 4.0 56.8
Roxithromycin 7.1 3.2 16.1 0.1 .
Clarithromycin 5.4 96.7 26.5 16.9 8.5
Azithromycin 20.8 92.1 34.3 25.8 4.1
Nitrofuran derivatives      
Nitrofurantoin 2.8 <0.1 2.1 17.0 2.3
Other antibacterials      
Fosfomycin . 9.2 0.6 0.2 .
Others 5.0 22.0 38.9 5.3 10.5
  1. aThe 12 most prescribed agents per database in 2008 were selected. Remaining agents were labelled as ‘others’.