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Table 3 Cardiometabolic risk factors of children and youth categorized as overweight/obese (OW/OB) and severely obese (SO)

From: Characterizing severe obesity in children and youth referred for weight management

 

OW/OB

SO

p-value

Triglycerides (mmol/L)

1.4 ± 0.8

1.5 ± 0.6

0.2

(n = 168)

(n = 147)

Total cholesterol (mmol/L)

4.5 ± 0.9

4.3 ± 0.8

0.03

(n = 168)

(n = 147)

HDL-cholesterol (mmol/L)

1.1 ± 0.3

1.0 ± 0.2

<0.001

(n = 168)

(n = 147)

LDL-cholesterol (mmol/L)

2.7 ± 0.8

2.6 ± 0.7

0.1

(n = 168)

(n = 147)

Total cholesterol/HDL ratio

4.3 ± 1.2

4.5 ± 1.1

0.2

(n = 168)

(n = 147)

ALT (U/L)

24.9 ± 16.0

31.6 ± 17.8

0.001

(n = 157)

(n = 145)

Fasting glucose (mmol/L)

4.9 ± 0.4

4.9 ± 0.4

0.7

(n = 159)

(n = 138)

Fasting insulin (mU/L)

18.5 ± 15.8

31.3 ± 20.4

0.02

(n = 154)

(n = 130)

HOMA-IR

4.0 ± 3.4

6.8 ± 4.6

0.03

(n = 151)

(n = 123)

Systolic BP (mmHg)

108 ± 9

115 ± 11

0.01

(n = 174)

(n = 150)

 

Diastolic BP (mmHg)

69 ± 8

72 ± 9

0.01

(n = 174)

(n = 150)

  1. Data are presented as mean ± standard deviation. HDL-C (high density lipoprotein cholesterol), LDL-C (low density lipoprotein cholesterol), ALT (alanine aminotransferase), HOMA-IR (homeostatic model assessment of insulin resistance).
  2. Note 1: Sample sizes vary variable-to-variable because dataset was incomplete.
  3. Note 2: Group comparisons for fasting glucose, fasting insulin, HOMA-IR, systolic BP and diastolic BP were completed using non-parametric analyses since these variables were not normally distributed.
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BMC Pediatrics

ISSN: 1471-2431

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