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Table 3 Cardiometabolic risk factors of children and youth categorized as overweight/obese (OW/OB) and severely obese (SO)

From: Characterizing severe obesity in children and youth referred for weight management

  OW/OB SO p-value
Triglycerides (mmol/L) 1.4 ± 0.8 1.5 ± 0.6 0.2
(n = 168) (n = 147)
Total cholesterol (mmol/L) 4.5 ± 0.9 4.3 ± 0.8 0.03
(n = 168) (n = 147)
HDL-cholesterol (mmol/L) 1.1 ± 0.3 1.0 ± 0.2 <0.001
(n = 168) (n = 147)
LDL-cholesterol (mmol/L) 2.7 ± 0.8 2.6 ± 0.7 0.1
(n = 168) (n = 147)
Total cholesterol/HDL ratio 4.3 ± 1.2 4.5 ± 1.1 0.2
(n = 168) (n = 147)
ALT (U/L) 24.9 ± 16.0 31.6 ± 17.8 0.001
(n = 157) (n = 145)
Fasting glucose (mmol/L) 4.9 ± 0.4 4.9 ± 0.4 0.7
(n = 159) (n = 138)
Fasting insulin (mU/L) 18.5 ± 15.8 31.3 ± 20.4 0.02
(n = 154) (n = 130)
HOMA-IR 4.0 ± 3.4 6.8 ± 4.6 0.03
(n = 151) (n = 123)
Systolic BP (mmHg) 108 ± 9 115 ± 11 0.01
(n = 174) (n = 150)  
Diastolic BP (mmHg) 69 ± 8 72 ± 9 0.01
(n = 174) (n = 150)
  1. Data are presented as mean ± standard deviation. HDL-C (high density lipoprotein cholesterol), LDL-C (low density lipoprotein cholesterol), ALT (alanine aminotransferase), HOMA-IR (homeostatic model assessment of insulin resistance).
  2. Note 1: Sample sizes vary variable-to-variable because dataset was incomplete.
  3. Note 2: Group comparisons for fasting glucose, fasting insulin, HOMA-IR, systolic BP and diastolic BP were completed using non-parametric analyses since these variables were not normally distributed.